Síndrome de glaucoma-apneia do sono

Glaucoma Respsosne to Lifestyle Corrections in Sleep Apnea

NCT07447011

RECRUTANDO

Obstructive Sleep Apnea as a Risk Factor for Normal Tension Glaucoma and a Crucial Step in Preventing Blindness

NCT06023927

EM ANDAMENTO

Advancing Understanding of Transportation Options

NCT04141891

CONCLUÍDO

Long-term Observation of Ophthalmic Changes in Patients With Obstructive Sleep Apnea

NCT03928665

EM ANDAMENTO

PAIR Study-PAP And IOP Relationship: Study 1

NCT03127813

DESCONHECIDO

🟢 Recrutando agora

1 pesquisa recrutando participantes. Converse com seu médico sobre a possibilidade de participar.

NCT07447011 · Glaucoma Respsosne to Lifestyle Corrections in Sleep ApneaRecrutando

NA

Outros ensaios clínicos

0 ensaios clínicos encontrados.

Distribuição por fase

NCT06023927 · Obstructive Sleep Apnea as a Risk Factor for Normal Tension …Em breve

NCT04141891 · Advancing Understanding of Transportation OptionsConcluído

NA

NCT03928665 · Long-term Observation of Ophthalmic Changes in Patients With…Ativo

NCT03127813 · PAIR Study-PAP And IOP Relationship: Study 1Encerrado

NA

Ver todos no ClinicalTrials.gov

🧪 Está conduzindo uma pesquisa?

Divulgue para pacientes e familiares que acompanham esta doença.

Divulgar pesquisa →

Publicações mais relevantes

📖Melhor nível de evidência: Revisão

Timeline de publicações

0 papers (10 anos)

#1

The Fontan Outcomes Network: Findings After 2 Years and 1121 Participants.

Circulation2026 Mar 25

Survival after Fontan palliation for single ventricle heart disease has improved substantially, yet the long-term trajectory remains poorly defined. The Fontan Outcomes Network, a learning health network of 38 congenital heart centers in the United States and Canada, was established to address this gap. We report baseline characteristics and early findings from the first 1121 participants enrolled in this prospective clinical registry. We performed a cross-sectional analysis of individuals who had undergone Fontan palliation enrolled in the Fontan Outcomes Network from August 2022 through August 2024. Demographic, clinical, imaging, procedural, and medication data were analyzed descriptively, overall and by age group (<12, 12 to <18, and ≥18 years). A total of 1121 participants were enrolled (mean age, 16.3±10.2 years; 471 [42%] female). Hypoplastic left heart syndrome (n=431 [38.5%]) and right ventricular-dominant anatomy (n=615 [54.9%]) were the most common primary cardiac diagnoses, especially in younger age groups. Extracardiac conduit was the most frequent Fontan type (n=749 [66.8%]). Typical Fontan-related adverse events were noted in 59% of cases (n=662), including chylous pleural effusions (n=108 [9.6%]), Fontan thrombosis (n=79 [7.1%]), and nonperioperative stroke (n=73 [6.5%]). A history of arrhythmia was present in 41.3% of patients (n=463) overall, increasing with age. Acquired comorbidities were present in 57.5% of patients (n=645), including asthma (n=132 [12%]) and sleep apnea (n=103 [9%]), with burden increasing by age. Antithrombotic medication use was nearly universal. Use of other medications varied widely by age, and included β-blockers, angiotensin-converting enzyme inhibitors, and pulmonary vasodilators. A clinical diagnosis of an anxiety disorder was present in 34.1% of patients (n=382), including 48.1% of adults (n=194 of 403), and antidepressants were prescribed in 11.8% of patients (n=132), including 23.6% of adults (n=95 of 403), highlighting the mental health needs of this population. The Fontan Outcomes Network includes one of the largest prospective, multi-institutional data sets of patients with Fontan circulation. These initial findings demonstrate the potential for a collaborative learning health network to advance research and quality improvement for this rare disease population.

#2

Diagnosis and Management of Overlap Syndrome (COPD-OSA): Evidence, Challenges and Prospects.

Nature and science of sleep2026

The overlap syndrome (OVS), characterized by the co-existence of obstructive sleep apnea (OSA) and chronic obstructive pulmonary disease (COPD), presents a significant clinical challenge due to its association with serious cardiopulmonary consequences and increased mortality. The complex pathophysiology and absence of standardized treatments often lead to underdiagnosis, aggravating its disease burden. Therefore, early and precise diagnosis is crucial. Beyond monitoring carbon dioxide levels as a key indicator of ventilatory limitation, a comprehensive diagnostic approach should integrate subjective assessments and objective examinations. Advances in precision medicine are shifting research focus towards biomarkers, including systemic inflammation ratios and vascular injury markers, to facilitate early detection and risk stratification. In terms of treatment, non-invasive ventilation (NIV) remains the cornerstone for maintaining airway patency, though its effectiveness is constrained by suboptimal adherence and inherent limitations. This has prompted the exploration of pharmacological strategies as alternatives or adjuncts, yet their application requires careful risk-benefit evaluation. For instance, benzodiazepines may worsen upper airway muscle tone and blunt hypercapnic arousal responses. Promising directions include novel pharmacotherapies inspired by recent advances in OSA treatment, alongside weight-loss agents that act through weight management and metabolic regulation. Adjunctive strategies such as mild intermittent hypoxia (IH) conditioning are being investigated to enhance positive airway pressure (PAP) therapy, while targeted agents like thioredoxin (TRX) demonstrate potential by mitigating oxidative stress and neutrophilic inflammation. However, the clinical translation of these innovations faces a major bottleneck the scarcity of large-scale randomized controlled trials (RCTs) to confirm their efficacy and safety. This review synthesizes current evidence to address these gaps and inform the future precision management of OVS.

#3

Lower fat-free mass is independently linked to restless legs syndrome in men: a cross-sectional PSG-BIA study.

Frontiers in neurology2026

Restless legs syndrome (RLS) is a common sensorimotor disorder that disrupts sleep and quality of life. Sarcopenia-reduced skeletal muscle mass and function-has been linked to sleep disturbances, but its relationship with RLS remains unclear. We examined whether sarcopenia is associated with RLS, with a focus on sex-specific effects. We conducted a cross-sectional analysis of 5,752 adults who underwent both type-I polysomnography (PSG) and bioelectrical impedance analysis (BIA) at a tertiary sleep center. RLS was diagnosed by IRLSSG criteria. Sarcopenia was defined using skeletal muscle index (SMI) and fat-free mass index (FFMI) thresholds. Multivariable models adjusted for age, physical activity, caffeine/alcohol intake, and apnea-hypopnea index (AHI). RLS prevalence was 6.6% in females and 2.9% in males. Sarcopenia was more frequent in the RLS group than in non-RLS (10.6 vs. 6.8%), particularly among males (8.7 vs. 3.2%). In males, lower SMI and FFMI were independently associated with higher odds of RLS; sex interaction for FFMI was significant. Reduced muscle mass is independently associated with RLS in men, suggesting a male-specific muscle phenotype relevant to RLS pathophysiology. Incorporating BIA-based screening and muscle-preserving interventions may benefit the management of male patients with RLS.

#4

Comparison of craniofacial skeletal morphology in pediatric obstructive sleep apnea-hypopnea syndrome patients with class II and class III malocclusions: a retrospective cross-sectional study.

Frontiers in pediatrics2026

This study aimed to investigate craniofacial skeletal morphology in pediatric obstructive sleep apnea-hypopnea syndrome (OSAHS) patients with different malocclusion types. A retrospective cross-sectional analysis study was conducted at Chengdu Second People's Hospital from 2023 to 2024. A total of 299 children diagnosed with OSAHS (aged 10-12 years) were included. Craniofacial structures were assessed using Jarabak and Ricketts methods. Patients were divided by malocclusion type: Class II (n = 150, 56.7% male, mean age 11.2 ± 0.6) and Class III (n = 149, 50.3% male, mean age 11.4 ± 0.8). Group differences in cephalometric parameters were compared using independent samples t-tests and Mann-Whitney U tests, as appropriate. Significant differences were found between groups. Compared to Class II, Class III patients had lower ANB angle (-2.8 ± 2.6° vs. 5.6 ± 1.9°, Cohen's d = 1.23), Wits appraisal (-2.9 ± 3.7 mm vs. 2.6 ± 0.7 mm, Cohen's d = 2.02), SN:GoMe (103.1 ± 6.0% vs. 106.7 ± 9.0%, Cohen's d = 0.48), MP/FH (32.9 ± 2.99° vs. 37.3 ± 2.65°, Cohen's d = 1.57), Xi-Pm/DC-Xi (29.3 ± 2.1° vs. 24.6 ± 3.1°, Cohen's d = 1.81), and ANS-Xi-Pm (47.8 ± 2.9° vs. 50.7 ± 2.4°, Cohen's d = 1.11) (all P < 0.05). Class III patients showed higher S-Ar:Ar-Go (75.9 ± 7.2% vs. 80.9 ± 13.0%, Cohen's d = 0.48), NP/FH (88.1 ± 2.9° vs. 83.1 ± 1.86°, Cohen's d = 2.14), Pt-Gn/Ba-N (92.2 ± 2.1° vs. 79.6 ± 2.4°, Cohen's d = 5.44), and Hy-C3 distance (5.8 ± 0.9 mm vs. 3.4 ± 0.4 mm, Cohen's d = 3.26) (all P < 0.05). No significant differences were observed in other parameters (N-S-Ar, S-Ar-Go; P > 0.05). Distinct craniofacial skeletal patterns exist in pediatric OSAHS patients with different malocclusions. Class III patients demonstrate mandibular growth restriction with compensatory protrusion, while Class II patients display high-angle, long-face morphology with clockwise growth rotation. These findings have important clinical implications for individualized orthodontic and surgical planning in the management of pediatric OSAHS, highlighting the need for early assessment of craniofacial structure in affected children.

#5

Understanding the impact of growth hormone on ventilatory control stability in children with Prader-Willi syndrome.

European journal of pediatrics2026 Mar 20

A hallmark of Prader-Willi syndrome (PWS) is hypothalamic-pituitary axis dysfunction, which can result in reduced growth hormone (GH) production. While GH replacement therapy is common in children with PWS, it has also been implicated in the development of obstructive sleep apnoea (OSA) in some children. The mechanisms underlying this development are poorly understood but may be related to alterations in ventilatory control. Our study investigated the impact of GH treatment on ventilatory control stability during sleep in children with PWS. Polysomnographic data pre- and post-GH therapy in 25 children (aged 2mo-18y) were used to assess ventilatory control using a validated method that estimates loop gain (dimensionless ratio) from ventilation changes following spontaneous sighs during sleep. Data were analysed using linear mixed-effects modelling with GH as a fixed effect and participant as a random intercept. Covariates that could impact loop gain including age, obstructive-apnoea hypopnoea index (OAHI) and central apnoea-hypopnoea index (CAHI) were each added separately to the base model in a stepwise, manual forward selection approach. Loop gain was not altered by GH treatment (β = 0.003, 95% CI: [-0.042, 0.049], p = 0.878, Cohen's d = 0.031). Age, OAHI and CAHI did not alter the impact of GH on loop gain. No difference in sleep or respiratory characteristics were found, however 20% of children developed OSA post-GH. Initiation of GH therapy was not associated with a change in loop gain, suggesting that changes in ventilatory control are unlikely to contribute to the development of OSA in children with PWS. • Prader-Willi syndrome is associated with abnormal ventilatory control and increased risk of sleep-disordered breathing. • Growth hormone therapy may influence respiratory physiology but its effect on the stability of ventilatory control (loop gain) remains unclear. • In this cohort of children with Prader-Willi syndrome, growth hormone therapy did not alter loop gain despite inter-individual variability. • Our findings suggest that any sleep-disordered breathing that emerges following growth hormone therapy is likely driven by mechanisms other than altered loop gain.

Publicações recentes

Management of COPD-OSA Overlap Syndrome Beyond Standard Care.

COPD2026 Dec

Risk Factors and Preceding Events Predisposing the Development of Superior Canal Dehiscence Syndrome.

Otol Neurotol2026 Jan 1

Are There Morphophysiological Airway Alterations in Syndromic Craniosynostosis? A 3D Computed Tomography and CFD Analysis.

💬 Opinião

Cleft Palate Craniofac J2026 Feb

Airway overlap syndromes with asthma.

📖 Revisão

Ann Allergy Asthma Immunol2026 Jan

Cognitive outcomes in chronic obstructive pulmonary disease (COPD)/OSA overlap syndrome compared to obstructive sleep apnea (OSA) alone: a systematic review.

Sleep Breath2025 Sep 1

Ver todas no PubMed

📚 EuropePMC1 artigos no totalmostrando 198

The Fontan Outcomes Network: Findings After 2 Years and 1121 Participants.

Circulation

Therapeutische Umschau. Revue therapeutique

[Sleep disorders and mental health].

Case Report: Immune checkpoint inhibitor-triggered anti-Ma2 paraneoplastic encephalitis in sarcomatoid pleural mesothelioma: a fatal case.

Frontiers in oncology

Nature and science of sleep

Diagnosis and Management of Overlap Syndrome (COPD-OSA): Evidence, Challenges and Prospects.

2026 Latin American consensus for the management of patients with hypertension and cardio-renal and metabolic disturbances: endorsed by the Latin American Society of Hypertension, the Iberoamerican Hypertension League, and the World Hypertension League.

Journal of hypertension

Sleep-Related Hypoventilation in a Patient With Ehlers-Danlos Syndrome.

Respiratory Syncytial Virus Infection Triggering a Pulmonary Hypertensive Crisis in a Boy With Prader-Willi Syndrome-Associated Sleep-Disordered Breathing.

Lower fat-free mass is independently linked to restless legs syndrome in men: a cross-sectional PSG-BIA study.

Frontiers in neurology

Comparison of craniofacial skeletal morphology in pediatric obstructive sleep apnea-hypopnea syndrome patients with class II and class III malocclusions: a retrospective cross-sectional study.

Frontiers in pediatrics

The prevalence of fibromyalgia syndrome in individuals with obstructive sleep apnea syndrome and the impact of continuous positive airway pressure treatment on fibromyalgia symptoms.

Relationship between body weight and daytime sleepiness in patients with untreated OSA: The role of hypoventilation due to obesity.

[Pulmometabolic syndrome: a review].

Terapevticheskii arkhiv

[Sleep disorders dynamics in patients with chronic thromboembolic pulmonary hypertension after surgical treatment].

Terapevticheskii arkhiv

European journal of pediatrics

Understanding the impact of growth hormone on ventilatory control stability in children with Prader-Willi syndrome.

Screening for paediatric sleep disordered breathing in the dental setting: a scoping review.

The Journal of craniofacial surgery

Complications of Adenotonsillectomy Surgery: Analysis of Pediatric Down Syndrome Patients in a Tertiary Center.

Journal of pharmacy & bioallied sciences

Association of Sleep Disorders with Temporomandibular Joint Pain Dysfunction Syndrome.

Addiction (Abingdon, England)

Latent classes of sleep deficiency and correlates among patients receiving methadone treatment: A longitudinal study.

Journal of cachexia, sarcopenia and muscle

Frailty and Recurrent Cardiovascular Events in Patients With Obstructive Sleep Apnoea: The SAVE Study.

COPD-sleep-disordered breathing overlap and vascular risk markers in non-obese adults: The Nagahama study.

Respiratory medicine

Screening for obstructive sleep apnea in an Afro-Caribbean Population: Diagnostic performance of common questionnaires compared with respiratory polygraphy - The MASOS Study A prospective, cross-sectional, descriptive, and analytical study.

Current medicinal chemistry

Biomarker-Based Analysis of the Association Between Obstructive Sleep Apnea Syndrome and Oxidative Stress: A Univariable, Bidirectional, and Multivariable Mendelian Randomization Study.

Journal of cardiac failure

Sleep Apnea in Heart Failure Patients with Preserved Ejection Fraction: Overlapping Syndromes, Negative Consequences: Sleep Apnea in HFpEF.

Free radical biology & medicine

ICAM-1 targeted extracellular vesicles loaded with HC-070 mitigate vascular oxidative stress and inflammation in obstructive sleep apnea hypopnea syndrome by inhibiting TRPC5.

Shared genetic architecture between sleep traits and cardiometabolic diseases.

EBioMedicine

Synergistic effects of short sleep duration and metabolic syndrome on major adverse cardiovascular events in older adults with obstructive sleep Apnea: A prospective cohort study.

Application of a knowledge, attitude, belief, and practice model in CPAP treatment of patients with OSAHS.

Respiratory medicine

The Relationship Between Chronic Intermittent Hypoxia and MASLD and Fibrosis in Obstructive Sleep Apnea Patients.

Serum Perilipin-2 as a Novel Biomarker for Obstructive Sleep Apnea: Association with Hypoxic Burden and Disease Severity.

Sleep health in the older adults: Architecture, circadian changes, and common sleep disorders.

Ageing research reviews

Sleep-disordered breathing in patients with heart failure with preserved left ventricular ejection fraction.

Neonatal Bradypnea as an Under-Recognized Manifestation of Prader-Willi Syndrome: A Case Report.

Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases

[Guidelines for the diagnosis and treatment of obstructive sleep apnea in adults (2025)].

The effect of tongue strength and endurance in patients with obstructive sleep apnea.

International journal of cardiology. Cardiovascular risk and prevention

Thrombaxane-B2 as a predictor marker of atrial fibrillation.

Recognition of a Critical Functional Domain and Improved PHOX2B Missense Variant Interpretation by Utilization of In Silico Prediction Tools.

Human mutation

Perioperative Challenges in a Patient With Sturge-Weber and Obesity Hypoventilation Syndromes.

Case reports in medicine

European journal of orthodontics

Dynamics of salivary stress-related biomarkers in children with malocclusion and risk for sleep problems and sleep-disordered breathing: a cross-sectional study.

Endotypic traits and lung function in patients with obstructive sleep apnea comorbid with obesity hypoventilation syndrome.

The journal of obstetrics and gynaecology research

Causal Associations Between Sleep Traits and Polycystic Ovary Syndrome: A Univariable, Bidirectional, and Multivariable Mendelian Randomization Study.

OSA is associated with enhanced coronary collateral circulation and reduced myocardial injury during acute coronary syndromes.

Chest

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

Echocardiographic effects of expansion sphincter pharyngoplasty in obstructive sleep apnea patients.

Dental and medical problems

Sleep-related respiratory impairment and psychosocial stress in patients with persistent orofacial pain: A cross-sectional exploratory study.

Sleep and circadian health in the UK Biobank: Report on the 2023 sleep questionnaire enhancement.

Sleep

Intravenous Sedation of a Patient With Morbid Obesity and Severe Sleep Apnea Syndrome for Dental Treatment: A Case Report.

Anesthesia progress

International journal of pediatric otorhinolaryngology

Clinical predictors of pediatric obstructive sleep apnea: Demographic and physical factors.

Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses

Long-term Efficacy of Health Belief Model Nursing Intervention in Preventing and Treating Moderate to Severe OSAHS in Postsurgery Patients.

Journal of lasers in medical sciences

Immediate Effect of LED Cluster on Masticatory Muscles in Children and Adolescents Diagnosed With Down Syndrome: A Pilot Study.

Acute hYpErcapnic respiratory failure in The ICU: A multicenter prospective observational study - The YETI study.

Annals of intensive care

International journal of dentistry

Effects of Andresen Activator on Pharyngeal Airway Volume in Growing Patients With Obstructive Sleep Apnea Syndrome: CBCT Evaluation.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

Temporary tracheotomy in transoral robotic surgery (TORS): from a retrospective single-center analysis to a proposal of a decision-making algorithm.

Obstructive sleep Apnea, lipoprotein(a) and long-term cardiovascular outcomes in acute coronary syndrome.

Sleep

Journal of dermatological science

Comprehensive analysis of tonsillar gene expression and the tonsillar microbiota in patients with palmoplantar pustulosis and pustulotic arthro-osteitis.

The European respiratory journal

Severe sleep-related hypoventilation in antibody-positive and antibody-negative autoimmune encephalitis: an emergency.

Arteriosclerosis, thrombosis, and vascular biology

Mechanisms Linking Sleep-Disordered Breathing and Cardiometabolic Disease Risk.

Effects of time-restricted eating on weight loss, sleep, and quality of life in obstructive sleep apnea-hypopnea syndrome (OSAHS) patients with obesity: a randomized controlled trial.

Frontiers in nutrition

Frontiers in cardiovascular medicine

Analysis of risk factors for early recurrence after radiofrequency ablation in patients with atrial fibrillation and construction of a nomogram predictive model.

Investigation of Possible Cardiac Manifestations of Dysautonomia in a Patient With Acquired Ondine's Curse Syndrome: A Rare Clinical Case Report.

Electroconvulsive Therapy in a Patient With Down Syndrome Regression Disorder and Inspire Device: A Case Report.

The journal of ECT

Analysis of Factors Influencing Extended Post Anesthesia Care Unit Length of Stay (PACU-LOS) in Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy.

Obesity surgery

Differences in upper airway endotype among phenotypically different pediatric OSA patients.

Obstructive Sleep Apnea-Hypopnea Syndrome in Children With Down Syndrome Treated at a Tertiary Care Hospital in Northeastern Colombia.

Computers in biology and medicine

Automatic sleep scoring for real-time monitoring and stimulation in individuals with and without sleep apnea.

Clinical and craniofacial predictors of patient-reported and respiratory outcomes with oral appliance therapy.

European journal of nutrition

Dietary behavior and its association with sleep-disordered breathing symptoms in Taiwanese children.

Advances in the Diagnosis and Treatment of Obstructive Sleep Apnea in Women.

Pulmonary therapy

The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

Screening for Obstructive Sleep Apnoea in Patients With Cleft Lip and/or Palate in Saudi Arabia.

Diabetes, obesity & metabolism

Tirzepatide Combined With Continuous Positive Airway Pressure Treatment in Obstructive Sleep Apnoea Syndrome With Comorbid Obesity: Effects on Weight, Daytime Sleepiness, and Cognitive Performance.

Remimazolam-based precision anesthesia management combined with nasopharyngeal airway in gastroscopic surgery for a patient with obesity and difficult airway: a successful case report.

Frontiers in medicine

Effect of Stellate Ganglion Block on Postoperative Pain in Patients with Obstructive Sleep Apnea Syndrome: A Randomized Controlled Trial.

Journal of pain research

Journal of the Indian Society of Pedodontics and Preventive Dentistry

Evaluation of salivary pH, buffering capacity, and total antioxidant capacity in children with sleep disorders.

Sensors (Basel, Switzerland)

Feasibility and Form Factor Validation of Reflective Shoulder-Mounted Pulse Oximeter in Patients with Suspected Sleep Apnea.

CPAP Treatment Exposure, but Not Daytime Sleepiness or Neurofilament Light Chain, Is Associated with Cognitive Performance in Obstructive Sleep Apnea.

Electrical Cardiometry as a Novel Tool for Assessing Systemic Vascular Resistance and Cardiac Function in Obstructive Sleep Apnea.

Life (Basel, Switzerland)

Electrocardiographic Alterations in Obstructive Sleep Apnea Syndrome: Mechanisms and Clinical Relevance.

Medicina (Kaunas, Lithuania)

Indoor Employment as a Factor Associated with Vitamin D Levels in Obstructive Sleep Apnoea Syndrome.

International journal of molecular sciences

Sleep-Disordered Breathing in Chung-Jansen Syndrome.

Tongue Pressure as a Predictor of Tongue Base Collapse in Patients with Obstructive Sleep Apnea Syndrome.

Biomedicines

Children (Basel, Switzerland)

Morphometric Findings in Adolescents with Robin Sequence: A Photographic and Cephalometric Study of the Face and Mandible.

Brain, behavior, and immunity

Neuroinflammation as a driver of Down syndrome-associated Alzheimer's disease.

Chronic intermittent hypoxia reshapes circadian metabolic architecture in a model of sleep apnea.

Science advances

American journal of respiratory and critical care medicine

Effectiveness of Automatically-adjusted vs. Manually-adjusted Noninvasive Ventilation in Obesity Hypoventilation Syndrome: A Randomized Clinical Trial.

Beyond the Apex: A Case Series of Mid-ventricular Takotsubo Cardiomyopathy.

Current opinion in neurology

SUDEP update 2026: recent advances in experimental and clinical research.

Neglected burden of obstructive sleep apnoea: workplace productivity loss in the USA and UK.

Thorax

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology

Shortest pulmonary vein atrial fibrillation cycle length identifies pulmonary vein isolation responders beyond clinical atrial fibrillation pattern: the FARS-AF II study.

Studies in health technology and informatics

Deep Learning-Based Sleep Apnea Classification with Hybrid 1D-CNN-LSTM and 1D-CNN-GRU Models.

Case reports in neurology

A Rare Case of Secondary Pseudotumor Cerebri Syndrome in a Female with a Tongue Base Tumor: A Case Report.

European journal of medical research

Electric stimulation and transcranial magnetic stimulation for obstructive sleep apnea.

The American journal of cardiology

Noninvasive Imaging Modalities for the Evaluation of Coronary Artery Disease Among Patients With High Body Mass Index: A Focus on Coronary Computed Tomography Angiography (CCTA).

Clinical and experimental hypertension (New York, N.Y. : 1993)

Mechanisms linking hypertension to cardiovascular and cerebrovascular diseases and their clinical implications: A comprehensive review.

Lung India : official organ of Indian Chest Society

Non-invasive ventilation in obstructive sleep apnoea/obesity hypoventilation syndrome: Experience from an Indian tertiary care respiratory centre.

Characterizing Sleep-disordered Breathing by Race and Ethnicity: Phenotypes, Risk, and Clinical Implications: Part 2.

Sleep medicine clinics

Characterizing Sleep-Disordered Breathing by Race and Ethnicity: Phenotypes, Risk, and Clinical Implications-Part 1.

Sleep medicine clinics

Disparities in Pediatric Sleep-Disordered Breathing.

Sleep medicine clinics

Obstructive sleep apnea increases recurrent cardiovascular event risk in younger but not older patients with acute coronary syndrome: a prospective cohort study.

Medical sciences (Basel, Switzerland)

Childhood Obesity: A Multisystem Challenge Linking Hypertension, NAFLD, and Sleep Apnea.

Advances in respiratory medicine

Differences in Causes, Severity, and Treatment Outcomes Between Women and Men with Chronic Cough.

Intelligent nanoliposome ameliorate chronic intermittent hypoxia-mediated neuronal injury via a dual regulation microglial inflammation strategy.

Materials today. Bio

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

Stage-specific interactions among PLM, RBD, and OSAHS in parkinson's disease and MSA.

Case reports in neurology

Tapia's Syndrome following Noninvasive Continuous Positive Airway Pressure Therapy: A Case Report.

Paediatric respiratory reviews

Long-term non-invasive ventilation in children with central nervous system disorders: A systematic review and meta-analysis.

Sleep apnea, heart health and testosterone: unravelling the triad of well-being.

EBioMedicine

The Journal of craniofacial surgery

Modified Osteotomies for Wing and Mini-Wing Genioplasty.

Sleep disorders in patients with juvenile myoclonic epilepsy: A polysomnographic investigation.

Epilepsy research

Antioxidants & redox signaling

Inhibition of TXNIP/NLRP3/GSDMD Pathway and Antioxidant Therapy Mitigate Cognitive Dysfunction Induced by Chronic Intermittent Hypoxia.

Compound heterozygous CHAT gene mutations, a missense and a splice site variant, in two siblings with congenital myasthenic syndrome.

Scientific reports

European journal of pediatrics

Incidence and risk factors of respiratory events after tonsillectomy for obstructive sleep apnea in children with a preoperative indication of intensive care unit admission.

Respiration; international review of thoracic diseases

Sex Differences in IPF: Data from the German INSIGHTS Registry.

Identification of Oral Protein Biomarkers for Cognitive Impairment Susceptibility in Obstructive Sleep Apnea: A Cross-Species Proteomic Study.

ACS omega

Severe Hypokalemia After Corticosteroid Use: A Case of Steroid-Induced Potassium Depletion.

Cardiofaciocutaneous Syndrome Type 4 due to a MAP2K2 Variant: Expanding the Phenotypic Spectrum With Feeding Dysfunction and Neurodevelopmental Involvement.

Clinical case reports

Dampened surge in heart rate at respiratory event termination in children with Prader-Willi syndrome.

Clinics (Sao Paulo, Brazil)

Obstructive sleep apnea in adults with Down syndrome: body composition, metabolic profile and cognitive status.

Multi-level surgery for obstructive sleep apnoea in syndromic and non-syndromic paediatric patients - A systematic review and meta-analysis.

International journal of pediatric otorhinolaryngology

Hematologic indices in pediatric sleep-disordered breathing: a retrospective case-control study.

European journal of neurology

Epidemiology and Economic Burden of Sleep Disorders in Europe.

Possible predictors of apneic-events during sleep: advanced snoring sound analysis.

Prevalence of coronary atherosclerosis in patients with obstructive sleep apnea syndrome: a systematic review and meta-analysis.

Evaluation of apelin, chemerin, leptin, resistin and vaspin levels in patients with obstructive sleep apnoea syndrome.

Multimodal ECG and biometric data fusion for improved detection of obstructive sleep apnea hypopnea syndrome.

Frontiers in medicine

Associations of Dietary Patterns and Physical Activity with Sleep Quality and Metabolic Health Markers in Patients with Obstructive Sleep Apnea: An Exploratory Pilot Study.

Nutrients

Beyond Sleep: The Cardiovascular Impact of Obstructive Sleep Apnea Syndrome.

Is Maxillomandibular Advancement Possible in Skeletal Class III Patients? A Scoping Review.

Sensors (Basel, Switzerland)

Early Screening of Sleep-Disordered Breathing Using a Smartphone-Based Portable System in Stroke Patients and Its Relevance for Rehabilitation: A Prospective Observational Study.

Diagnostics (Basel, Switzerland)

Research Progress and Clinical Practice in the Comorbidity Management of Obstructive Sleep Apnea Hypopnea Syndrome and Obesity Hypopnea Syndrome.

Clinical subtypes of co-morbid insomnia and obstructive sleep apnea (COMISA): results of a cluster analysis.

Respiratory research

Activation of M1mAChR's improves spatial learning and memory deficits in rats exposed to chronic intermittent hypoxia.

Scientific reports

Obstructive sleep apnea as a potential mechanistic link between second-generation antipsychotics and metabolic syndrome: a narrative review.

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine

Effect of self-viewing of sleep-apnoea videos on positive airway pressure adherence in moderate to severe obstructive sleep apnoea: a prospective, parallel-group, randomised controlled trial.

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine

Awake speech recordings for machine learning diagnosis of obstructive sleep apnea: a Bayesian meta-analysis.

Sleep-Disordered Breathing in Cystic Fibrosis in Low- and Middle-Income Countries.

Pediatric pulmonology

Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery

Paediatric Adenoidectomy: A Retrospective Cohort Study of Clinical Practice and Outcomes in NHS England (2008-2024).

Archives of medical science : AMS

Associations between leisure sedentary behaviors, physical activity, and chronic respiratory diseases: a Mendelian randomization study.

Archives of medical science : AMS

Causal association between sleep traits and diabetic nephropathy.

International journal of qualitative studies on health and well-being

Navigating sleep apnea in Scandinavia - a journey of contrasts.

Polysomnography Dataset for Sleep Analysis in Ischemic Stroke Patients.

Scientific data

Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery

The role of metabolic and bariatric surgery in managing severe obesity in children with special health care needs and syndromic obesity.

Evaluation of an automated sleep apnea scoring algorithm via the Wesper Lab home sleep apnea test.

Circadian gene expression in adolescents: Associations with concurrent circadian disruption and subsequent changes in cardiometabolic risk measures.

SOMAS - an open-source software for the analysis of muscle activity during sleep.

IEEE journal of biomedical and health informatics

Radar-Based Monitoring for Non-Contact Detection of Nocturnal Hypoglycemia in Diabetes: A Review.

Expert-level probabilistic breathing event detector informs phenotyping of sleep apnea.

Nature communications

Current hypertension reports

Insomnia and Hypertension: Importance of Objective Phenotyping and Comorbidity with Sleep Apnea.

The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

The Most Efficient Surgical Technique to Treat Velopharyngeal Insufficiency After Primary Cleft Palate Repair: A Systematic Review and Meta-Analysis.

Frontiers in endocrinology

Association between sleep apnea-specific novel hypoxic metrics and disturbances in glucose and lipid metabolism.

Sleep advances : a journal of the Sleep Research Society

SARS-CoV-2 infection and sleep health in Military Health System beneficiaries.

Reviews in cardiovascular medicine

Resistant Hypertension: Integration of Novel Agents and Interventional Approaches in Clinical Practice.

Journal of clinical orthopaedics and trauma

Early onset scoliosis in syndromic and neuromuscular disorders: A multidisciplinary approach.

Frontiers in aging neuroscience

Impact of obstructive sleep apnea on gut microbiome of patients with symptomatic intracranial atherosclerotic stenosis.

Frontiers in cardiovascular medicine

The correlation between reactive hyperemia index and endothelial dysfunction markers in patients with hypertension and obstructive sleep apnea syndrome: a cross-sectional study.

Nationwide trends in pediatric obesity in Thailand, 2015-2023: prevalence, morbidity, mortality, and COVID-19-related disparities.

BMC public health

European annals of otorhinolaryngology, head and neck diseases

Pediatric obstructive sleep apnea hypopnea diagnosis using a video recording score: A pilot study.

Journal of translational medicine

Targeting GLP1 receptor for reducing global cardiovascular risk.

Population-based Characterization of PTEN Hamartoma Tumor Syndrome.

Research square

Sex differences in self-reported symptoms and comorbidities associated with hypermobile Ehlers-Danlos syndrome and hypermobility spectrum disorders: A retrospective study.

Research square

Journal of applied physiology (Bethesda, Md. : 1985)

Estrogen receptor alpha determines sex-specific cardiorespiratory and autonomic responses to intermittent hypoxia in mice.

A patient with anti-IgLON5 disease associated with cerebral hemorrhage, multiple ischemic strokes, and kidney failure: case report.

Journal of neurology

The diagnostic yield of a structured comorbidity workup in a real-life outpatient population with obstructive sleep apnea: a cross-sectional study.

Annals of medicine

Italian journal of pediatrics

Dexmedetomidine for LISA procedure: a prospective observational single center experience.

Characterization of Retinal Microvascular Changes in Obstructive Sleep Apnea Using OCT Angiography: Data from the Obstructive Sleep Apnea and Retinal Microvascular NETwork Study.

Ophthalmology

Nederlands tijdschrift voor tandheelkunde

[Obstructive sleep apnoea in children with Down s syndrome: challenges and treatment strategies].

Nederlands tijdschrift voor tandheelkunde

[The organization of sleep apnoea care in the Netherlands].

The impact of paediatric periodic limb movement disorder and obstructive sleep apnoea syndrome on sleep quality and daytime symptoms.

Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases

[Annual review of advances in sleep-disordered breathing 2025].

The Journal of craniofacial surgery

Effects of Xinghanxiang Nasal Inhalation Therapy on Obstructive Sleep Apnea-Hypopnea Syndrome and Upper Airway Inflammation.

Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995)

A Statistical Study of Attention Deficit/Hyperactivity Disorder, Attention Deficit Disorder, and Hyperactivity and Their Relation to Sleep-Disordered Breathing.

Self-Powered Wireless System for Sleep Apnea Syndrome Self-Management Using π-Conjugated Poly(benzodifurandione)-Based Low-Hysteresis Humidity Sensors and Highly Sensitive Pressure Sensors.

ACS sensors

Journal of sleep research

Urinary Metabolomic Profiling in Obstructive Sleep Apnoea Hypopnoea Syndrome.

Profiling metabotropic glutamate receptor 7 expression in Rett syndrome: consequences for pharmacotherapy.

Neuroscience

Screening and Management of Sleep Disorders in Patients with Fibromyalgia Syndrome: A French Multicenter, Prospective, Observational Study.

Pain and therapy

Severity and phenotype of sleep-disordered breathing in Prader-Willi syndrome compared to obstructive sleep apnea syndrome in children.

Respiratory medicine

Research in developmental disabilities

Sleep in children with spinal muscular atrophy and their caregivers: Exploring sleep problems and the need for care.

Desaturations with or without Bradycardia Are Associated with Cerebral and Abdominal Hypoxemia: Secondary Analysis of a Randomized Clinical Trial.

Neonatology

Ear, nose, & throat journal

Metabolic and Anthropometric Factors Outperform Psychomotor Vigilance Task in Predicting Obstructive Sleep Apnea in Pilots: A LASSO-Based Analysis.

International ophthalmology

The impact of obstructive sleep apnea syndrome on corneal sensitivity and dry eye parameters: a comprehensive analysis.

Life (Basel, Switzerland)

Impact of Pressure Variability and Comorbidities on PAP Therapy Compliance and Adherence in Obstructive Sleep Apnea.

Children (Basel, Switzerland)

Obesity Hypoventilation Syndrome in Children and Adolescents.

Bioengineering (Basel, Switzerland)

Generative Adversarial Networks for Modeling Bio-Electric Fields in Medicine: A Review of EEG, ECG, EMG, and EOG Applications.

Clinical effects of the use of a novel oropharyngeal airway in painless gastroscopy in patients with obstructive sleep apnoea-hypopnoea syndrome: a randomised controlled trial protocol.

BMJ open

Modulation-Based Feature Extraction for Robust Sleep Stage Classification Across Apnea-Based Cohorts.

Biosensors

Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery

[Correlation between serum IgE antibodies to allergens and OSAHS in pediatric patients with tonsillar adenoid hypertrophy].

Journal of human nutrition and dietetics : the official journal of the British Dietetic Association

The Content of Dietary Melatonin in 119 Food Items and Its Relationship With Chronic Diseases: Results of the CUME+ Study.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia

Excessive daytime sleepiness in patients with idiopathic normal pressure hydrocephalus: A controlled cross-sectional study.

Association between high loop gain sleep apnea detected by respiratory self-similarity and left ventricular remodeling.

Journal of voice : official journal of the Voice Foundation

Voice Outcomes after Expansion Sphincter Pharyngoplasty in Patients with Obstructive Sleep Apnea Syndrome.

Association of standard postoperative day 1 discharge following endonasal surgery for pituitary adenoma with lower complication rates and unplanned medical care.

Journal of neurosurgery

Acta paediatrica (Oslo, Norway : 1992)

Age Does Not Affect Respiratory Characteristics in Children With Prader-Willi Syndrome Before and After Growth Hormone Therapy.

Association between pre-operative adherence to positive airway pressure therapy and postoperative opioid use after lower limb arthroplasty in patients with obstructive sleep apnoea.

Anaesthesia reports

Beyond Snoring: Unexpected Presentation of Obstructive Sleep Apnea.

Sleep-Disordered Breathing in Newborns After Myelomeningocele Repair.

Pediatrics

Sleep apnea and substance use: a meta-analysis.

Sleep medicine reviews

Oxygen Saturation Sample Entropy, a Novel Diagnostic Tool in Sleep Disordered Breathing.

Lung

Mandibular Distraction Osteogenesis Guided by 3D Model and Monitored with Ultrasonography: A Case Report.

Pediatric reports

Clinical toxicology (Philadelphia, Pa.)

Respiratory and cardiac toxicity of xylazine and fentanyl overdose in rats.

Intranasal Treatments for Children With Sleep-Disordered Breathing: The MIST+ Randomized Clinical Trial.

JAMA pediatrics

Management of Patients with Asthma, COPD, and OSA in Outpatient Unit: ACOSOU-Global Perspectives and Challenges.

Pulmonary therapy

Próxima:Tire suas dúvidas

Assessment of Sleep-Disordered Breathing and Sleep Quality in Childhood Interstitial Lung Disease: A Single-Center Experience.

Pediatric pulmonology

Próxima:Associações

Associações

Organizações que acompanham esta doença — pra ter apoio e orientação

Ainda não temos associações cadastradas para Síndrome de glaucoma-apneia do sono.

É de uma associação que acompanha esta doença? Fale com a gente →

Próxima:Comunidades

Comunidades

Grupos ativos de quem convive com esta doença aqui no Raras

Ainda não existe comunidade no Raras para Síndrome de glaucoma-apneia do sono

Pacientes, familiares e cuidadores se organizam em comunidades pra compartilhar experiências, fazer perguntas e se apoiar. Você pode ser o primeiro.

Tire suas dúvidas

Perguntas, dicas e experiências compartilhadas aqui na página

Participe da discussão

Faça login para postar dúvidas, compartilhar experiências e interagir com especialistas.

Fazer login

Próxima:Doenças relacionadas

Doenças relacionadas

Doenças com sintomas parecidos — ajudam quem ainda está buscando diagnóstico

Ordenadas pelo número de sintomas em comum.

Síndrome Ehlers-Danlos vascular

3 em comum

ORPHA:286

Nanismo geleofísico

3 em comum

ORPHA:2623

Síndrome Aicardi-Goutieres

ORPHA:51

Síndrome Walker-Warburg

Síndrome Carey-Fineman-Ziter

ORPHA:899

Síndromes miastênicas, congênitas, sinápticas

ORPHA:1358

Síndromes miastênicas, congênitas, pós-sinápticas

ORPHA:98915

Síndrome de neuropatia motora axonal distal-miopatia fibrilar autossômica dominante

ORPHA:98913

Síndrome de microcefalia congênita-encefalopatia grave-atrofia cerebral progressiva

ORPHA:476093

Síndrome angio-osteohipertrófica

ORPHA:391376

Síndrome Ehlers-Danlos espondilodisplásico B4GALT7-relacionado

ORPHA:2346

Síndrome otopalatodigital tipo 2

ORPHA:75496