The role of a multidisciplinary approach in non-melanoma skin cancer management.

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model.

A Meier-Gorlin syndrome mutation impairs the loading of the MCM2-7 complex during DNA replication initiation.

Identification of a PORCN c.1093C>T (p.Arg365Trp) Variant in a 12-Year-Old Girl With Goltz-Gorlin Syndrome.

[Research advance on the clinical phenotypes and molecular genetic mechanisms of Microcephalic primordial dwarfism].

Molecular diagnosis of rare biallelic CDC45 gene variants causing Meier-Gorlin syndrome-7 using whole exome sequencing.

Meier-Gorlin syndrome due to a recurrent DONSON variant in a Turkish family: first report of thumb aplasia and long-term growth data.

AlphaFold3 predictions of novel GLI-SUFU interfaces identify binding-defective SUFU missense variants from medulloblastoma and Gorlin Syndrome patients.

Resection of intracardiac tumors in infants.

A Presentation of Fungating Nevoid Basal Cell Carcinoma Syndrome.

Molecular impacts of Meier-Gorlin syndrome mutations on human origin licensing.

Clinical practice guidelines for the management of basal cell carcinoma in Gorlin syndrome.

Basaloid Proliferations in Palmar Lesions of Gorlin Syndrome: A Distinct Entity or Precursor Lesion?

Clinical and Molecular Study of a Gorlin Syndrome Type 1 Case.

Clinical challenges of cancer predisposition syndromes with pediatric central nervous system tumors: a single-center study.

Does Basal Cell Carcinoma Arise from a Precursor Lesion?

A case of basal cell nevus syndrome with a SUFU mutation.

Synchronous Cardiac Fibroma and Medulloblastoma in Gorlin Syndrome: A Paradigmatic Case and Narrative Review.

Anesthetic management in a child with Meier-Gorlin syndrome: a case report.

Clinical and genetic findings in 103 individuals in Norway with basal cell naevus syndrome.

Multicenter Retrospective Case Series on the Real-World Experience With Sonidegib for the Management of Gorlin Syndrome.

Low-dose oral minoxidil for the management of vismodegib-induced alopecia.

A camouflaged carcinoma and it's surgical encounter - A case report.

Unexpected molecular mechanism of Orc6-based Meier-Gorlin syndrome: insights from a humanized Drosophila model.

Congenital Absence of Bilateral Patella in an Active Military Personnel Case Report.

A Novel PTCH1 Non-Canonical Splice Region Variant Associated with Gorlin Syndrome: A Case Report.

Clinical Features and PTCH1 Expression in Gorlin-Goltz Syndrome: A Case Report.

Gorlin-Goltz syndrome: Multidisciplinary approach for early diagnosis of rare disease for better patient outcome.

Skin Signals: Exploring the Intersection of Cancer Predisposition Syndromes and Dermatological Manifestations.

Vitiligo-associated protection against basal cell carcinoma: Clinical observations.

Mutational analysis of the Drosophila CMG helicase reveals relationships among chromosome integrity and the maintenance of spindle and centrosome structure.

Subtypes of basal cell carcinomas in adults with basal cell nevus syndrome: A retrospective review.

Eight-Year Experience of Hedgehog Pathway Inhibitors at Three Tertiary Referral Centres in the Australian State of Victoria.

At the mercy of my condition: a patient perspective on living with Gorlin syndrome.

Diagnostic Yield of Exome Sequencing for Pregnancies With and Without Fetal Anomalies and for Stillbirth.

A Case of Sustained Ventricular Tachycardia Secondary to a Cardiac Fibroma in a Patient With Gorlin Syndrome.

Worth the Effort: Lessons for Discovery and Care From an Unusual Case of Gorlin Syndrome.

Nonsyndromic epidermal differentiation disorders: a new classification toward pathogenesis-based therapy.

Syndromic epidermal differentiation disorders: a new classification toward pathogenesis-based therapy.

Effects of CDC45 mutations on DNA replication and genome stability.

Palmoplantar epidermal differentiation disorders: a new classification toward pathogenesis-based therapy.

A 12-Year-Old Female With Facial Bumps, Body Pits, and Coiled Scalp Hair.

Determining the Relationship Between Cutaneous Keratocysts and Basal Cell Nevus Syndrome.

Early onset basal cell carcinoma: Consider Bazex-Dupré-Christol syndrome.

A Clinical Trial to Determine the Impact of Tumor Size, Histological Subtype, and Vitamin D Status on the Therapeutic Response of Basal Cell Carcinoma to Photodynamic Therapy.

Patidegib: a novel, promising treatment for basal cell carcinoma lesions in patients with Gorlin syndrome.

Nevoid basal cell carcinoma syndrome (Gorlin syndrome): a case report.

A novel homozygous intronic variant in CDT1 that alters splicing causes Meier-Gorlin syndrome, and a review of published mutations and growth hormone treatments.

Surgical management of ovarian fibromas in young patients with Gorlin syndrome: a case series and review of the literature.

Clinicopathological and molecular insights into odontogenic tumors associated with syndromes: A comprehensive review.

Metastatic basal cell carcinomas in Gorlin syndrome-A case series and literature review.

Clinical Challenges in Diagnosing Primordial Dwarfism: Insights from a MOPD II Case Study.

Analysis of Germline and Somatic Mutation in Patients With Developmental Odontogenic Cysts Using Targeted Gene Panel.

Topical application of the Hedgehog inhibitor patidegib in patients with Gorlin syndrome: a phase II trial.

Use of Anti-PD1 Blockade After Hedgehog Inhibitors or as First-Line Therapy for Gorlin Syndrome.

Re-evaluation of the concept of basaloid follicular hamartoma associated with naevoid basal cell carcinoma syndrome: a morphological, immunohistochemical and molecular study.

Exploration of the causative gene in a case of multiple nevoid basal cell carcinoma: A case report.

Brain morphological analysis in mice with hyperactivation of the hedgehog signaling pathway.

Clinicopathological and molecular spectrum of patients with germline SUFU mutations: A case series.

Phenotypes, Genetics, and Estimated Prevalence of Focal Dermal Hypoplasia (Goltz Syndrome): A Single-Center Report.

Proteome-scale characterisation of motif-based interactome rewiring by disease mutations.

Intrauterine growth in chromatinopathies: A long road for better understanding and for improving clinical management.

Developing expert consensus for the use of hedgehog inhibitors in basal cell nevus syndrome.

Oral smoothened inhibitors for Gorlin syndrome: A clinical review.

Meier-Gorlin syndrome type 7: a rare cause of primordial dwarfism: two new cases and literature review.

Gorlin Syndrome-Associated Basal Cell Carcinomas Treated with Vismodegib or Sonidegib: A Retrospective Study.

Germline PTCH1: c.361_362insAlu alteration identified by comprehensive exome and RNA sequencing in a patient with Gorlin syndrome.

Further Expanding the Mutational Spectrum of Gorlin Syndrome in Three Unrelated Families.

A Long-Term Follow-Up of a Patient with a Novel PORCN Variant and Additional Clinical Features.

Skin cancer-associated genodermatoses in skin of color patients: a review.

Functional studies in yeast confirm the pathogenicity of a new GINS3 Meier-Gorlin syndrome variant.

Clinical vs. molecular diagnosis of Gorlin syndrome: relevance of diagnostic criteria depends on the age of the patients.

Assessment of Mammalian Target of Rapamycin Pathway Activation in Basal Cell Carcinoma as a New Therapeutic Approach.

PERIOCULAR HIGH RISK BCCS AFTER ADDITIONAL/PARALLEL INTAKE OF TORASEMIDE, MOXONIDINE AND MIRABEGRON: IMPORTANT LINKS TO SKIN CANCER RELATED (PHOTO-) NITROSOGENESIS IN THE CONTEXT OF PHARMACO-ONCOGENESIS.

A second hotspot for pathogenic exon-skipping variants in CDC45.

Gorlin Syndrome: A Comprehensive Evaluation of Skin Findings.

Postmortem 7T MRI in Goltz-Gorlin Syndrome: Insights into fetal anomalies beyond conventional imaging techniques.

Digital pathology-based artificial intelligence models for differential diagnosis and prognosis of sporadic odontogenic keratocysts.

Pediatric odontogenic keratocyst and early diagnosis of Gorlin syndrome: Clinicopathological aids.

Dentofacial manifestations of a Paediatric patient with Goltz-Gorlin Syndrome.

Gorlin-Like Phenotype in a Young Girl With a De Novo PTCH2 Variant Mutation of Uncertain Significance.

Defining the progeria phenome.

Medulloblastoma and other neoplasms in patients with heterozygous germline SUFU variants: A scoping review.

The Origin Recognition Complex: From Origin Selection to Replication Licensing in Yeast and Humans.

Genetics of Cardiac Tumours: A Narrative Review.

DONSON: Slding in 2 the limelight.

Acquisition of Drug Resistance in Basal Cell Nevus Syndrome Tumors through Basal to Squamous Cell Carcinoma Transition.

Hedgehog Inhibitors Beyond Clinical Complete Response in Basal Cell Carcinoma: Should I Stop or Should I Go?

Photodynamic Therapy in Treating a Subset of Basal Cell Carcinoma: Strengths, Shortcomings, Comparisons with Surgical Modalities, and Potential Role as Adjunctive Therapy.

Exploring the Changing Diagnostic Criteria of Gorlin-Goltz Syndrome: A Case Report.

Loss-of-function of zebrafish cdt1 causes retarded body growth and underdeveloped gonads resembling human Meier-Gorlin syndrome.

An Institutional Experience of a Tertiary Referral Center in Surgically Managing Patients With Gorlin Syndrome.

Bilateral ovarian fibromas as the sole manifestation of Gorlin syndrome in a 22-year-old woman: a case report and literature review.

Sustained Suppression of Gorlin Syndrome-Associated Basal Cell Carcinomas with Vismodegib or Sonidegib: A Case Series.

Case Report: Papillary thyroid carcinoma in Goltz-Gorlin syndrome.

Tolerance of sonidegib after intolerance of vismodegib-Experience in two patients with nevoid basal cell carcinoma syndrome (Gorlin syndrome).

DONSON is required for CMG helicase assembly in the mammalian cell cycle.

A novel de novo canonical splice site mutation in the PTCH1 gene in a male patient with mild psychomotor retardation and autistic traits: a case report.

[Genetic analysis of a child with Meier-Gorlin syndrome due to a variant of ORC6 gene].

DONSON facilitates Cdc45 and GINS chromatin association and is essential for DNA replication initiation.

Hedgehog-Related Mutation Causes Bone Malformations with or without Hereditary Gene Mutations.

Incidence and Prevalence of 73 Different Genodermatoses: A Nationwide Study in Sweden.

European consensus-based interdisciplinary guideline for diagnosis and treatment of basal cell carcinoma-update 2023.

Gorlin Syndrome and Cowden Syndrome.

Whole-Exome Sequencing Identified Two Novel Pathogenic Mutations in the PTCH1 Gene in BCNS.

Brain and/or Spinal Cord Tumors Accompanied with Other Diseases or Syndromes.

Isolated frontosphenoidal craniosynostosis: An argument for genetic testing.

De novo MCM6 variants in neurodevelopmental disorders: a recognizable phenotype related to zinc binding residues.

Fine Wine or Stale Bread: The Aging Emergency Physician.

A Novel Method to Reconstruct the Upper and Lower Jaws Using 3D-Custom-Made Titanium Implants.

Surveillance of a large cardiac fibroma in a patient with Gorlin syndrome.

An Easily Missed But Life-Threatening Diagnosis: A Case Report of Gorlin Syndrome.

Understanding Nevoid Basal Cell Carcinoma Syndrome (Gorlin Syndrome): A Case Report.

Sonidegib as a Locally Advanced Basal Cell Carcinoma Therapy in Real-life Clinical Setting: A National Multicentre Study.

The expanding genetic and clinical landscape associated with Meier-Gorlin syndrome.

Perspectives on the implications of carrying putative pathogenic variants in the medulloblastoma predisposition genes ELP1 and GPR161.

Modeling human cancer predisposition syndromes using CRISPR/Cas9 in human cell line models.

A case of Gorlin syndrome like phenotype with multiple infundibulocystic basal cell carcinomas in a moniliform blepharosis arrangement.

Association of Meier-Gorlin and microcephalic osteodysplastic primordial dwarfism type II clinical features in an individual with CDK5RAP2 primary microcephaly.

SUFU-associated Gorlin syndrome: Expanding the spectrum between classic nevoid basal cell carcinoma syndrome and multiple hereditary infundibulocystic basal cell carcinoma.

Cardiac Fibroma Presenting With Left Bundle Branch Block in an Adult With Gorlin Syndrome.

Imaging of Bifid Fourth Rib Presenting as a Chest Wall Mass in an Infant.

A novel biallelic CRIPT variant in a patient with short stature, microcephaly, and distinctive facial features.

Characterization of intractable diarrhea resulting from vismodegib treatment for basal cell nevus syndrome.

Defining patient-centered research priorities in pediatric dermatology.

Pediatric Cutaneous Oncology: Genodermatoses and Cancer Syndromes.

Molecular Mechanisms and Targeted Therapies of Advanced Basal Cell Carcinoma.

A 10-year follow-up on the chemopreventive role of photodynamic therapy in a Gorlin syndrome patient.

Early-onset basal cell carcinoma; wide case series at a single tertiary center in middle Anatolia.

Utility of optical coherence tomography in basal cell naevus syndrome: A case report.

Gorlin Syndrome Associated With a Solitary Circumscribed Retinal Astrocytic Proliferation in a Pediatric Patient.

Predictive factors of response to vismodegib: a French study of 61 patients with multiple or locally advanced basal cell carcinoma.

Nervous system (NS) Tumors in Cancer Predisposition Syndromes.

Clinical Impact of Cardiac Fibromas.

Photodynamic therapy in pediatric age: Current applications and future trends.

Meier-Gorlin Syndrome: Clinical Misdiagnosis, Genetic Testing and Functional Analysis of ORC6 Mutations and the Development of a Prenatal Test.

Advances in Management and Therapeutics of Cutaneous Basal Cell Carcinoma.

PTCH1 mutant small cell glioblastoma in a patient with Gorlin syndrome: A case report.

Patient and caregiver perspectives on delayed childhood Gorlin syndrome diagnoses.

Ovarian tumors and genetic predisposition.

Multidisciplinary approach to Gorlin-Goltz syndrome: from diagnosis to surgical treatment of jawbones.

Gorlin syndrome - Case report.

Case report of bilateral ovarian fibromas associated with de novo germline variants in PTCH1 and SMARCA4.

Basal Cell Carcinoma and Hedgehog Pathway Inhibitors: Focus on Immune Response.

Ovarian fibroma as a novel indicator for burden of basal cell carcinoma in women with Gorlin syndrome: a retrospective cross-sectional analysis of the Gorlin syndrome national patient registry.

Experience with sonidegib in patients with advanced basal cell carcinoma: case reports.

Hypomorphic GINS3 variants alter DNA replication and cause Meier-Gorlin syndrome.

Pediatric synchronous multifocal and disseminated cerebrospinal classic medulloblastoma revealed by bilateral decreased visual acuity: a case report.

An investigation of metabolic disturbances, including urinary stone disease, hypothyroidism, and osteoporosis in basal cell nevus syndrome.

Multidisciplinary neurocutaneous syndrome clinics: a systematic review and institutional experience.

Update on Hedgehog Pathway Inhibitor Therapy for Patients with Basal Cell Naevus Syndrome or High-frequency Basal Cell Carcinoma.

Development of a targeted gene panel for the diagnosis of Gorlin syndrome.

Leiomyomatosis in an Infant With a SUFU Splice Site Variant: Case Report.

Gorlin Syndrome: Assessing Genotype-Phenotype Correlations and Analysis of Early Clinical Characteristics as Risk Factors for Disease Severity.

Nevoid basal cell carcinoma syndrome with anophthalmia: a case report.

Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Familial Tumor Syndromes.

Microcephalic primordial dwarfism with predominant Meier-Gorlin phenotype, ichthyosis, and multiple joint deformities-Further expansion of DONSON Cell Cycle-opathy phenotypic spectrum.

Meier-Gorlin syndrome with prenatal ultrasound findings and successful growth hormone therapy: Six years follow-up of a rare case.

Topical hedgehog inhibitors for basal cell carcinoma: how far away are we?

Hairy patches as early dermatological signs of Gorlin syndrome in a patient with a novel PTCH1 genetic variant.

Gorlin Syndrome: Sequential Digital Dermoscopy of Palpebral Basal Cell Carcinomas in a Patient Treated with Vismodegib.

Novel uses of laser therapy in Goltz syndrome.

Novel Compound Heterozygous Variants in the CDC6 Gene in a Russian Patient with Meier-Gorlin Syndrome.

Meningothelial Hamartoma of the Scalp in a Child With Gorlin Syndrome.

Cancer-Predisposition Genetic Analysis in Children with Brain Tumors Treated at a Single Institution in Japan.

Angioma-serpiginosum-like and hyperkeratotic lesions in a patient with Goltz syndrome.

Bilateral ovarian fibromas in a 15-year-old primary amenorrhea patient: a case report.

Calcified Ovarian Fibromas Complicated with Basal Cell Nevus Syndrome.

Defining the Spectrum, Treatment and Outcome of Patients With Genetically Confirmed Gorlin Syndrome From the HIT-MED Cohort.

Evaluation of Hedgehog Pathway Inhibition on Nevoid Basal Cell Carcinoma Syndrome Fibroblasts and Basal Cell Carcinoma-Associated Fibroblasts: Are Vismodegib and Sonidegib Useful to Target Cancer-Prone Fibroblasts?

Pediatric basal cell carcinoma burden and management preferences in Gorlin syndrome: A survey study.

How to manage patients with Gorlin syndrome.

Tumor Syndromes: Neurosurgical Evaluation and Management.

Neurosurgical Considerations of Neurocutaneous Syndromes.

Novel alterations in IFT172 and KIFAP3 may induce basal cell carcinoma.

Nevoid basal cell carcinoma syndrome: a case report and literature review.

Bifid rib with fused vertebrae - A rare abnormality of the skeletal system: A case report.

Presence of circulating tumor cells in a patient with multiple invasive basal cell carcinoma - a case report.

Biallelic GINS2 variant p.(Arg114Leu) causes Meier-Gorlin syndrome with craniosynostosis.

Dental and orthodontic follow-up in nevoid basal cell carcinoma syndrome patient with odontogenic keratocystic tumors.

PTCH2 is not a strong candidate gene for gorlin syndrome predisposition.

Cardiac fibroma with cardiac arrest: a rare clinical presentation of Gorlin syndrome in an 8-month-old infant.

The molecular coupling between substrate recognition and ATP turnover in a AAA+ hexameric helicase loader.

Prenatal diagnosis of Meier-Gorlin syndrome 7: a case presentation.

Gorlin syndrome: A rare case report.

Microdeletion of 9q22.3: A patient with minimal deletion size associated with a severe phenotype.

Basal cell nevus syndrome with excessive basal cell carcinomas.

Differences in RNA and microRNA Expression Between PTCH1- and SUFU-mutated Medulloblastoma.

Current recommendations for cancer surveillance in Gorlin syndrome: a report from the SIOPE host genome working group (SIOPE HGWG).

Multiple basal cell carcinomas in Gorlin Syndrome treated with pulsed dye laser.

Current update on the molecular genetics and management of hereditary ovarian cancers: a primer for radiologists.

A Novel Case of Gorlin Syndrome Mosaicism Involving an SMO Gene Mutation: Clinical, Histological and Molecular Analysis of Basaloid Tumours.

Concurrent basal cell carcinoma and tarsal epithelial cyst as a presenting sign of Gorlin syndrome.

MCM complex members MCM3 and MCM7 are associated with a phenotypic spectrum from Meier-Gorlin syndrome to lipodystrophy and adrenal insufficiency.

A synonymous variant in a non-canonical exon of CDC45 disrupts splicing in two affected sibs with Meier-Gorlin syndrome with craniosynostosis.

De Novo PORCN and ZIC2 Mutations in a Highly Consanguineous Family.

Congenital Diseases of DNA Replication: Clinical Phenotypes and Molecular Mechanisms.

An incidental finding of intraocular choristoma in an enucleated microphthalmic globe: A histopathologic case report.