Van der Woude syndrome with novel variants: a case series.

Distinct IRF6 dysfunction mechanisms in syndromic orofacial clefts: Computational evidence for allosteric versus direct disruption.

Haploinsufficiency of GRHL2 is associated with orofacial clefting in humans.

Rare variants in PRKCI cause Van der Woude syndrome and other features of peridermopathy.

EMG1 cooperates with GRHL3 in β-catenin-mediated surface ectoderm differentiation to regulate neural tube closure.

Van Der Woude in Unilateral Cleft Lip: Phenotypic Patterns and Surgical Adaptations.

Neural crest and periderm-specific requirements of Irf6 during neural tube and craniofacial development.

Van der Woude syndrome and amniotic band sequence: A clue to a common genetic etiology? A case report.

Popliteal Pterygium Syndrome with a Family History of Van der Woude Syndrome: A Case Report.

DNA Methylation Effects on Van der Woude Syndrome Phenotypic Variability.

Programmed RNA editing with an evolved bacterial adenosine deaminase.

Surgical Treatment of Lip Pits in Van der Woude Syndrome: A Preliminary Retrospective Study of 24 Patients.

A novel IRF6 gene mutation impacting the regulation of TGFβ2-AS1 in the TGFβ pathway: A mechanism in the development of Van der Woude syndrome.

Rare Congenital Upper Lip Pit.

Congenital midline upper lip sinus in an infant.

[Analysis of a Chinese pedigree affected with van der Woude syndrome due to variant of IRF6 gene].

Van Der Woude Syndrome: A Case Series at Chu D' Treichville, Abidjan, Cote D' Ivoire.

Non-syndromic Oligodontia in Primary Dentition: A Report of a Rare Case.

A Complex Intrachromosomal Rearrangement Disrupting IRF6 in a Family with Popliteal Pterygium and Van der Woude Syndromes.

Hospitalizations from Birth to 28 Years in a Population Cohort of Individuals Born with Five Rare Craniofacial Anomalies in Western Australia.

DNA methylation differences in monozygotic twins with Van der Woude syndrome.

A Comprehensive Genetic Analysis of Slovenian Families with Multiple Cases of Orofacial Clefts Reveals Novel Variants in the Genes IRF6, GRHL3, and TBX22.

Causal Variations at IRF6 Gene Identified in Van der Woude Syndrome Pedigrees.

Novel IRF6 variant in orofacial cleft patients from Durban, South Africa.

Van der Woude Syndrome and Alopecia Areata: More Than a Fortuitous Association?

Association of single nucleotide polymorphisms in the IRF6 gene with nonsyndromic cleft lip with or without cleft palate in Kinh Vietnamese patients.

Novel de novo missense mutation in the interferon regulatory factor 6 gene in an Italian infant with IRF6-related disorder.

Craniofacial characteristics in Van der Woude syndrome.

Lower lip pits with sinus tracts in Van der Woude syndrome: a case report and review of the literature.

Rare and Multiple Hypodontia in Van der Woude Syndrome: Case Report.

Mutations in Van Der Woude Families From Ethiopia.

Distribution and risk factors of cleft lip and palate on patients from a sample of Damascus hospitals - A case-control study.

Popliteal Pterygium With Van Der Woude Syndrome.

Dental age, agenesis, and morphological anomalies in individuals with Van der Woude syndrome and isolated cleft palate.

Altered regulation of cell migration in IRF6-mutated orofacial cleft patients-derived primary cells reveals a novel role of Rho GTPases in cleft/lip palate development.

A Novel IRF6 Frameshift Mutation in a Large Chinese Pedigree With Van der Woude syndrome.

Clinical Findings and Outcomes of Palatal Repair in 9 Patients With Van der Woude Syndrome.

Screening of IRF6 Variants in Patients Subjected to Genetic Association Studies for Nonsyndromic Cleft Lip/Palate.

A Novel Van der Woude Syndrome-Causing IRF6 Variant Is Subject to Incomplete Non-sense-Mediated mRNA Decay Affecting the Phenotype of Keratinocytes.

A clinical and multi‑omics study of Van der Woude syndrome in three generations of a Chinese family.

Technique for assisting excision of labial fistula in van der Woude syndrome.

A Synonymous Exonic Splice Silencer Variant in IRF6 as a Novel and Cryptic Cause of Non-Syndromic Cleft Lip and Palate.

Change in Initial Tympanostomy Tube Placement Timing Yields Decreased Burden of Care Without Increased Complications in Patients With Cleft Lip and Palate.

Functional Characterization of a Novel IRF6 Frameshift Mutation From a Van Der Woude Syndrome Family.

Taurodontism in the first permanent molars in Van der Woude syndrome compared to isolated cleft palate.

Non-random distribution of deleterious mutations in the DNA and protein-binding domains of IRF6 are associated with Van Der Woude syndrome.

Epithelial Migration and Non-adhesive Periderm Are Required for Digit Separation during Mammalian Development.

Novel IRF6 mutations in Chinese Han families with Van der Woude syndrome.

[Genetic analysis of a family of Van der Woude syndrome].

Interferon regulatory factor 6 is required for proper wound healing in vivo.

Meta-Analysis of Grainyhead-Like Dependent Transcriptional Networks: A Roadmap for Identifying Novel Conserved Genetic Pathways.

The RIPK4-IRF6 signalling axis safeguards epidermal differentiation and barrier function.

Hemiscrotal agenesis with complete testicular descent in Van der Woude syndrome: a new phenotypic feature.

Van der Woude Syndrome: IRF6 Mutations.

Patients With Cleft Lip and Palate Associated With Intraoral Fibrous Bands: A Report of 3 Cases and Review of Literature.

Van der Woude Syndrome With a Novel Mutation in the IRF6 Gene.

Surgical, Speech, and Audiologic Outcomes in Patients With Orofacial Cleft and Van der Woude Syndrome.

Novel mutations of IRF6 gene in Taiwanese Van der Woude syndrome patients.

Microdeletion of the entire IRF6 gene in a Subsaharian African's family with Van der Woude syndrome.

Congenital lower lip pits: Van der Woude syndrome.

[Clinical and genetic features of Chinese kindreds with Van der Woude syndrome caused by interferon regulatory factor 6 mutation].

Diagnosis of Tooth Agenesis in Childhood and Risk for Neoplasms in Adulthood.

Keratinocytes Isolated From Individual Cleft Lip/Palate Patients Display Variations in Their Differentiation Potential in vitro.

Congenital midline sinus of the upper lip: A case report and review of literature.

Van der Woude and Popliteal Pterygium Syndromes.

IRF6 and AP2A Interaction Regulates Epidermal Development.

Combined Tongue-Palate Fusion With Alveolar Bands in a Patient With Pierre Robin Sequence and Van der Woude Syndrome.

Genetic heterogeneity in Van der Woude syndrome: identification of NOL4 and IRF6 haplotype from the noncoding region as candidates in two families.

Identification of somatic mutations in monozygotic twins discordant for psychiatric disorders.

Clinical, histomorphological and therapeutic features of the Van der Woude Syndrome: literature review and presentation of an unusual case.

A novel non-coding RNA within an intron of CDH2 and association of its SNP with non-syndromic cleft lip and palate.

Whole exome sequencing identifies mutations in 10% of patients with familial non-syndromic cleft lip and/or palate in genes mutated in well-known syndromes.

SCLERAL PITS IN CHOROIDEREMIA: Implications for Retinal Gene Therapy.

Association between genotype and phenotype of virulence gene in Van der Woude syndrome families.

Treatment of lower lip pits in Van der Woude syndrome: a systematic review.

Tracheal dilatation as sign of fetal airway obstruction in case of oral cavity tumor.

LONG-TERM FOLLOW-UP OF PATIENTS WITH CHOROIDEREMIA WITH SCLERAL PITS AND TUNNELS AS A NOVEL OBSERVATION.

Surgical management of lower lip pits in Van der Woude syndrome.

Loss-of-Function GRHL3 Variants Detected in African Patients with Isolated Cleft Palate.

Van der Woude syndrome presenting as a single median lower lip pit with associated dental, orofacial and limb deformities: a rare case report.

Disrupted IRF6-NME1/2 Complexes as a Cause of Cleft Lip/Palate.

IRF6 and SPRY4 Signaling Interact in Periderm Development.

Grainyhead-like Transcription Factors in Craniofacial Development.

IRF6 expression in basal epithelium partially rescues Irf6 knockout mice.

Generation and characterization of a conditional allele of Interferon Regulatory Factor 6.

The prevalence, penetrance, and expressivity of etiologic IRF6 variants in orofacial clefts patients from sub-Saharan Africa.

Concurrent Van der Woude syndrome and Turner syndrome: A case report.

Genetic Factors in Selected Complex Congenital Malformations with Cleft Defect.

Multidisciplinary management of a patient with van der Woude syndrome: A case report.

Shared molecular networks in orofacial and neural tube development.

Novel IRF6 Mutations Detected in Orofacial Cleft Patients by Targeted Massively Parallel Sequencing.

Lack of Association between Missense Variants in GRHL3 (rs2486668 and rs545809) and Susceptibility to Non-Syndromic Orofacial Clefts in a Han Chinese Population.

Management of Lip Pits in Van der Woude Syndrome: A Clinical Classification With Difficulty Index.

Van der Woude and Popliteal Pterygium Syndromes: Broad intrafamilial variability in a three generation family with mutation in IRF6.

Palatoglossal fusion with cleft palate and hypoplasia of cerebellar vermis.

A Novel Interferon Regulatory Factor 6 Mutation in an Asian Family With Van der Woude Syndrome.

Association study between Van der Woude Syndrome causative gene GRHL3 and nonsyndromic cleft lip with or without cleft palate in a Chinese cohort.

A peripherally inserted central line in a preterm infant.

Interferon Regulatory Factor 6 Controls Proliferation of Keratinocytes From Children With Van der Woude Syndrome.

Sequencing the GRHL3 Coding Region Reveals Rare Truncating Mutations and a Common Susceptibility Variant for Nonsyndromic Cleft Palate.

Ankyloglossia with cleft lip: A rare case report.

Complex intrachromosomal rearrangement in 1q leading to 1q32.2 microdeletion: a potential role of SRGAP2 in the gyrification of cerebral cortex.

Irf6 directly regulates Klf17 in zebrafish periderm and Klf4 in murine oral epithelium, and dominant-negative KLF4 variants are present in patients with cleft lip and palate.

IRF6 mutation screening in non-syndromic orofacial clefting: analysis of 1521 families.

Toward an orofacial gene regulatory network.

Congenital midline sinus of the upper lip.

Disease-associated mutations in IRF6 and RIPK4 dysregulate their signalling functions.

Genome-wide copy number scan identifies IRF6 involvement in Van der Woude syndrome in an Indian family.

Congenital Symmetrical Lower Lip Pits: Van der Woude Syndrome.

A Japanese family with popliteal pterygium syndrome.