A síndrome de Cronkhite-Canada (CCS) é uma síndrome rara de polipose gastrointestinal (GI) caracterizada pela associação de polipose GI não hereditária com a tríade cutânea de alopecia, alterações ungueais e hiperpigmentação.
Introdução
O que você precisa saber de cara
A síndrome de Cronkhite-Canada (CCS) é uma síndrome rara de polipose gastrointestinal (GI) caracterizada pela associação de polipose GI não hereditária com a tríade cutânea de alopecia, alterações ungueais e hiperpigmentação.
Escala de raridade
<1/50kMuito rara
1/20kRara
1/10kPouco freq.
1/5kIncomum
1/2k
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Sinais e sintomas
O que aparece no corpo e com que frequência cada sintoma acontece
Partes do corpo afetadas
+ 17 sintomas em outras categorias
Características mais comuns
Os sintomas variam de pessoa para pessoa. Abaixo estão as 50 características clínicas mais associadas, ordenadas por frequência.
Linha do tempo da pesquisa
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Genética e causas
O que está alterado no DNA e como passa nas famílias
Nenhum gene associado encontrado
Os dados genéticos desta condição ainda estão sendo catalogados.
Diagnóstico
Os sinais que médicos procuram e os exames que confirmam
Tratamento e manejo
Remédios, cuidados de apoio e o que precisa acompanhar
Onde tratar no SUS
Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)
🇧🇷 Atendimento SUS — Síndrome Cronkhite-Canada
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Publicações mais relevantes
Diarrhea-Associated Hypovolemic Shock due to Cronkhite-Canada Syndrome.
Cronkhite-Canada syndrome.
A comprehensive literature-based analysis of prognosis in patients with Cronkhite-Canada syndrome.
Cronkhite-Canada syndrome (CCS) is a rare, nonhereditary gastrointestinal disorder with unclear etiology and limited treatment consensus. Given the scarcity of data, we aimed to construct a pooled literature-based cohort to analyze survival outcomes and identify prognostic factors to inform future therapeutic strategies. We developed a literature-based cohort of Cronkhite-Canada syndrome by extracting individual patient data from published case reports and two in-house cases. Articles were selected through a systematic screening process based on relevance and data availability. Information collected included age, sex, clinical symptoms, laboratory findings, endoscopic and histological features, treatment approaches, and outcomes. The compiled dataset was used to explore clinical characteristics, treatment patterns, and survival trends across reported cases. A total of 200 CCS patients were analyzed, including 198 from literature and 2 in-house cases. Most patients presented with diarrhea, weight loss, skin pigmentation, and alopecia. Polyps were commonly found in the stomach and colon. Survival analysis showed a 1-year survival rate of 92.3% and a 3-year survival rate of 79.9%. Male sex was associated with poor prognosis. However, multivariate analysis showed no significant predictors. Treatment with corticosteroids significantly improved survival, especially with high doses (≥ 40 mg/day). Surgical intervention tended to correlate with poorer outcomes. These findings suggest that appropriately dosed corticosteroid therapy may enhance long-term prognosis in CCS. Using a comprehensive analysis of literature-based Cronkhite-Canada syndrome cases and our in-house cases, this study demonstrated the clinical characteristics of CCS. Our data showed the prognostic value of sex and surgical intervention, and the significance of high dose corticosteroid therapy on the treatment of CCS.
Cronkhite-Canada syndrome, hypothyroidism and positive autoantibodies: a case report.
Cronkhite-Canada Syndrome is an exceptionally rare, sporadic disorder of unknown etiology characterized by hamartomatous gastrointestinal polyps, ectodermal changes, and malabsorption. Reporting this case is crucial owing to its rarity, the associated positive autoantibodies, and the patient's remarkable response to combined therapy, which adds valuable insight to the limited data on Cronkhite-Canada syndrome management. A 59-year-old Pakistani male presented with chronic diarrhea, weight loss, nail dystrophy, and hyperpigmentation. Clinical examination, endoscopic findings, and histological analysis confirmed the diagnosis of Cronkhite-Canada syndrome, with positive autoantibodies and associated hypothyroidism. The patient was treated with prednisolone, mesalazine, and azathioprine, leading to dramatic improvements, including resolution of diarrhea and polyposis, weight gain, nail regrowth, and reduced hyperpigmentation. Laboratory parameters normalized, and the patient remained in remission off treatment. This case highlights the importance of recognizing Cronkhite-Canada syndrome's clinical, endoscopic, and histological features. The patient's excellent response to immunosuppressive therapy underlines its potential as an effective treatment strategy, offering valuable insights into managing this rare condition.
Cronkhite-Canada syndrome after corticosteroid and mesalazine treatment: A case report and 3-year follow-up.
Cronkhite-Canada syndrome (CCS) is a rare, nonhereditary gastrointestinal polyposis syndrome with known malignant potential. This case report aims to present the clinical course, management, and long-term (3-year) follow-up of a CCS patient, highlighting the discrepancy between symptomatic improvement and endoscopic progression, and to discuss associated carcinogenic risk. A 50-year-old man presented with diffuse abdominal pain of unclear origin, bloody stools, hair loss, melanosis on the hands, and nail dystrophy. Laboratory tests revealed hypoalbuminemia, hypocalcemia, hypokalemia, and positive fecal occult blood. Enteroscopy and subsequent pathological examination confirmed the presence of characteristic intestinal polyps, leading to a diagnosis of CCS. The patient was treated with a continuous regimen of corticosteroids combined with mesalazine. After 1 year of medical therapy, he underwent endoscopic mucosal resection. The patient's clinical symptoms improved significantly following treatment. However, endoscopic and pathological findings showed a tendency to deteriorate over time. At the 3-year follow-up, this disparity between clinical well-being and pathological progression persisted. CCS carries a risk of malignant transformation. Even with clinical improvement on long-term corticosteroid and mesalazine therapy, endoscopic progression may occur. Therefore, we recommend intensive endoscopic surveillance every 3 to 6 months following initial diagnosis, maintained for at least the 1st year, as a strategy to mitigate cancer risk.
Publicações recentes
Diarrhea-Associated Hypovolemic Shock due to Cronkhite-Canada Syndrome.
🥉 Relato de casoA comprehensive literature-based analysis of prognosis in patients with Cronkhite-Canada syndrome.
Cronkhite-Canada syndrome, hypothyroidism and positive autoantibodies: a case report.
🥇 Meta-análiseCronkhite-Canada syndrome after corticosteroid and mesalazine treatment: A case report and 3-year follow-up.
An Uncommon Cause of Refractory Chronic Diarrhea.
📚 EuropePMC360 artigos no totalmostrando 155
Diarrhea-Associated Hypovolemic Shock due to Cronkhite-Canada Syndrome.
The American journal of gastroenterologyA comprehensive literature-based analysis of prognosis in patients with Cronkhite-Canada syndrome.
DigestionCronkhite-Canada syndrome, hypothyroidism and positive autoantibodies: a case report.
Journal of medical case reportsCronkhite-Canada syndrome after corticosteroid and mesalazine treatment: A case report and 3-year follow-up.
MedicineAn Uncommon Cause of Refractory Chronic Diarrhea.
GastroenterologyCronkhite-Canada syndrome.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the LiverCronkhite-Canada Syndrome With Multiple Mesenteric Lymphadenopathy: A Case Report.
JGH open : an open access journal of gastroenterology and hepatologyVedolizumab as a Second Line Biologic for Cronkhite Canada Syndrome and an Approach Toward Disease Monitoring.
ACG case reports journalCronkhite-Canada syndrome presenting with chronic diarrhea: A case report.
MedicineA case of idiopathic portal hypertension complicated by cronkhite-canada syndrome presenting with refractory ascites.
Fukushima journal of medical scienceA Case of Ascending Colon Cancer Complicated by Cronkhite-Canada Syndrome Treated with Robot-Assisted Right Hemicolectomy.
Surgical case reportsAn Unusual Presentation of Cronkhite-Canada Syndrome With Hypothyroidism.
Case reports in medicineA Case of Asymptomatic Cronkhite-Canada Syndrome Diagnosed by Endoscopic and Pathological Findings.
CureusMyelodysplastic Syndrome in a Patient With Cronkhite-Canada Syndrome.
Clinical case reportsCronkhite-Canada Syndrome Presenting as Diarrhea and Weight Loss: A Case Report and Literature Review.
The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chiArrhythmias in Cronkhite-Canada Syndrome.
Internal medicine (Tokyo, Japan)Infliximab treatment for Cronkhite-Canada syndrome in pregnancy: A case report.
Case reports in women's healthRespondence of steroid predicts the long-term clinical and endoscopic prognosis in Cronkhite-Canada syndrome.
QJM : monthly journal of the Association of PhysiciansA Rare Case of Cronkhite-Canada Syndrome in a Moroccan Female Patient.
CureusUnraveling a Rare Case: Diarrhea, Alopecia, and Polyposis.
Gastroenterology[A Case of Cronkhite-Canada Syndrome Associated with Transverse Colon Cancer].
Gan to kagaku ryoho. Cancer & chemotherapyClinical features of taste disorders in Cronkhite-Canada syndrome: a report of 10 cases.
Chemical sensesEfficacy and safety of azathioprine in patients with Cronkhite-Canada syndrome: a case series from Peking Union Medical College Hospital.
BMC pharmacology & toxicologyCronkhite-Canada syndrome: A case report and literature review.
MedicineCase Report: Cronkhite-Canada syndrome: presentation of a pediatric case and review of the literature.
Frontiers in pediatricsCronkhite-Canada syndrome tends to be accompanied by colorectal cancer: Report of seven cases.
JGH open : an open access journal of gastroenterology and hepatologyCronkhite-Canada syndrome complicated with pulmonary embolism: A case report.
World journal of clinical casesA case of membranous nephropathy complicated by Cronkhite-Canada syndrome successfully treated with mizoribine.
CEN case reportsCronkhite-Canada Syndrome With Advanced Gastric Cancer.
ACG case reports journalSpontaneous remission of Cronkhite-Canada syndrome without immunosuppressive medication in the context of decompensated cirrhosis: A case report.
Clinical case reportsSustained remission of Cronkhite-Canada syndrome after corticosteroid and mesalazine treatment: A case report.
World journal of clinical casesPolyposis of gastrointestinal tract after COVID-19 mRNA vaccination: a report of two cases.
Clinical endoscopyCronkhite-Canada Syndrome: A Rare Cause of Gastrointestinal Polyposis With Response to Emerging Therapy.
ACG case reports journalCronkhite-Canada syndrome with esophagus involvement and six-year follow-up: A case report.
World journal of gastroenterologyCronkhite-Canada syndrome: An atypical presentation with subungual hyperkeratosis.
JAAD case reportsRecurrent nocturnal hypoglycemic hemiplegia: a case report and review of the literature.
Endocrine journal[A Rare Case of Cronkhite-Canada Syndrome Associated with Gastric Cancer and Gastric Outlet Obstruction].
Gan to kagaku ryoho. Cancer & chemotherapyCronkhite‒Canada syndrome as inflammatory hamartomatous polyposis: new evidence from whole transcriptome sequencing of colonic polyps.
Orphanet journal of rare diseasesComprehensive treatment and a rare presentation of Cronkhite-Canada syndrome: Two case reports and review of literature.
World journal of gastrointestinal surgeryA case report of Cronkhite-Canada syndrome first encounterd at a hospital in northern Vietnam.
Annals of medicine and surgery (2012)Human intestinal organoids from Cronkhite-Canada syndrome patients reveal link between serotonin and proliferation.
The Journal of clinical investigationCronkhite-Canada Syndrome Masquerading as Inflammatory Bowel Disease.
ACG case reports journalNarrow-band imaging with magnification for the diagnosis of colorectal adenoma in a patient with Cronkhite-Canada syndrome.
DEN openClinical and Endoscopic Response to Anti-Tumor Necrosis Factor-Alpha Antibody Therapy in a Patient With Cronkhite-Canada Syndrome.
Journal of investigative medicine high impact case reportsEndoscopic features help to identify the histopathological patterns of colorectal polyps in Cronkhite-Canada syndrome.
Journal of digestive diseasesAnalyses of cytokine gene expression and fecal microbiota in a patient with Cronkhite-Canada syndrome successfully treated with prednisolone.
DEN openAn Unusual Case of Diarrhea, Dysgeusia, and Grainy and Nodular Mucosa.
GastroenterologyCronkhite-Canada Syndrome- The first case from Pakistan: a case report.
JPMA. The Journal of the Pakistan Medical AssociationDeep vein thrombosis in a patient with Cronkhite-Canada syndrome: a complex case report.
Thrombosis journalComprehensive treatment of Cronkhite-Canada syndrome: A case report and literature review.
MedicineCronkhite-Canada syndrome: treatment responses and improved overall survival.
International journal of colorectal diseaseThe Use of Deep Snare Biopsies to Diagnose Cronkhite-Canada Syndrome.
ACG case reports journalCronkhite-Canada syndrome: First case report from Egypt and North Africa.
World journal of gastrointestinal endoscopyCronkhite-Canada Syndrome: A Rare Case of Chronic Diarrhea With Ectodermal Changes.
CureusCronkhite-Canada Syndrome Mimicking COVID-19-related Symptoms.
Acta dermato-venereologicaThalidomide combined with endoscopy in the treatment of Cronkhite-Canada syndrome: A case report.
World journal of clinical casesDermoscopic and histological findings in Cronkhite-Canada syndrome: a report of two cases.
International journal of dermatologyExome analysis for Cronkhite-Canada syndrome: A case report.
World journal of clinical casesCronkhite-Canada syndrome: A case report and review of the literature.
Annals of medicine and surgery (2012)Dermatological and Gastrointestinal Manifestations of Cronkhite-Canada Syndrome.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary TractA case of Cronkhite-Canada syndrome with repeated linked color imaging observation of the subepithelial capillary network in the colon.
Clinical journal of gastroenterologyDiffuse Gastrointestinal Polyposis With Skin, Hair, and Nail Changes.
GastroenterologyThe genomic landscape of Cronkhite-Canada syndrome: Possible clues for pathogenesis.
Journal of digestive diseasesCronkhite-Canada Syndrome: A Case Report.
JNMA; journal of the Nepal Medical AssociationHair Loss and Polyposis in Cronkhite-Canada Syndrome.
Gastro hep advancesCronkhite-Canada Syndrome Associated With Superficial Esophageal Carcinoma: A Case Report and Literature Review.
Frontiers in medicineThe first report on effect of fecal microbiota transplantation as a complementary treatment in a patient with steroid-refractory Cronkhite-Canada syndrome: A case report.
MedicineSurgery for Cronkhite-Canada syndrome complicated with intussusception: A case report and review of literature.
World journal of gastrointestinal surgeryCronkhite-Canada syndrome: a retrospective analysis of four cases at a single medical center.
Scandinavian journal of gastroenterology[Cronkhite-Canada syndrome].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterologyAn Unusual Case of Gastrointestinal Polyposis.
GastroenterologyEndoscopic and Pathological Characteristics of Cronkhite- Canada Syndrome: A Retrospective Analysis of 76 Cases.
The Turkish journal of gastroenterology : the official journal of Turkish Society of GastroenterologyGastrointestinal polyposis with associated cutaneous manifestations.
PathologyCronkhite-Canada syndrome: An investigation in clinical features and pathogenesis.
Journal of digestive diseasesCronkhite-Canada Syndrome: A rare Case Report from Nepal.
Journal of Nepal Health Research CouncilPolypoid lesions in the stomach and the colon: Cronkhite-Canada syndrome.
The lancet. Gastroenterology & hepatologyEndoscopic Images before the Onset of Cronkhite-Canada Syndrome.
Internal medicine (Tokyo, Japan)Cronkhite-Canada syndrome with steroid dependency: A case report.
World journal of clinical casesAplastic Anemia in a Patient with Cronkhite-Canada Syndrome.
Internal medicine (Tokyo, Japan)Endoscopic ultrasound-guided rendezvous with a combination of 22-gauge needle and 0.018-inch guidewire for acute cholangitis with Cronkhite-Canada syndrome.
Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy SocietyCronkhite-Canada Syndrome: A Rare COVID-19 Mimicker.
The American journal of gastroenterologyCronkhite-Canada syndrome associated with perianal condyloma acuminatum with malignant transformation: A case report.
Medicine[Cronkhite–Canada syndrome].
Orvosi hetilapEndoscopic features of Cronkhite-Canada syndrome.
EndoscopyClinical and Endoscopic Characteristics of Chinese Cronkhite-Canada Syndrome Patients: A Retrospective Study of 103 Cases.
Digestive diseases (Basel, Switzerland)Sustained clinical response to infliximab in refractory Cronkhite-Canada syndrome.
BMJ case reportsCronkhite-Canada Syndrome Successfully Treated by Corticosteroids before Presenting Typical Ectodermal Symptoms.
Case reports in gastroenterologyNausea and Diarrhea with Fingernail and Hair Changes.
GastroenterologyCronkhite-Canada syndrome: from clinical features to treatment.
Gastroenterology reportA case of Helicobacter pylori-negative gastric cancer associated with Cronkhite-Canada Syndrome.
Clinical journal of gastroenterology[Weight loss, diarrhea and dystrophic alterations of the fingernails in an 80-year-old male patient].
Der InternistCronkhite-Canada Syndrome Associated with Gastric Outlet Obstruction and Membranous Nephropathy: A Case Report and Review of the Literature.
Internal medicine (Tokyo, Japan)Cronkhite-Canada syndrome: report of a rare case and review of the literature.
The Journal of international medical research[Endoscopic features and clinical correlation analysis of 24 patients with Cronkhite-Canada syndrome].
Zhonghua yi xue za zhiSuccessful surgical treatment of Cronkhite-Canada Syndrome with bilateral flail chest: a case report.
BMC surgeryThe Long-Term Clinical and Endoscopic Outcomes of Cronkhite-Canada Syndrome.
Clinical and translational gastroenterologyBlue laser imaging in a patient with Cronkhite-Canada syndrome.
Gastrointestinal endoscopyEstimated Prevalence of Cronkhite-Canada Syndrome, Chronic Enteropathy Associated With SLCO2A1 Gene, and Intestinal Behçet's Disease in Japan in 2017: A Nationwide Survey.
Journal of epidemiologyCronkhite-Canada syndrome in an adult with titanium orthopaedic implants.
Journal of the European Academy of Dermatology and Venereology : JEADVA case of papilloma-like lesions of the esophagus in Cronkhite-Canada syndrome.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the LiverCronkhite-Canada syndrome complicated with three malignant tumors: a case report and whole exome sequencing analysis.
Chinese medical journalIleal intussusception and perforation associated with Cronkhite-Canada syndrome.
ANZ journal of surgeryA Successful Steroid-Sparing Approach in Cronkhite-Canada Syndrome.
ACG case reports journalDiarrhoea, Hyperpigmentation and Hamartomatous Polyposis Syndrome.
The Journal of the Association of Physicians of IndiaAlopecia in Cronkhite-Canada syndrome: Is it truly telogen effluvium?
The Australasian journal of dermatologyCase report of patient with a Cronkhite-Canada syndrome: sustained remission after treatment with corticosteroids and mesalazine.
BMC gastroenterologyMajor duodenal papilla prolapse in Cronkhite-Canada syndrome.
EndoscopyA Case Report of Cronkhite-Canada Syndrome Complicated by Membranous Nephropathy.
Case reports in nephrology and dialysis[Clinicopathologic features of Cronkhite-Canada syndrome and the significance of IgG4-positive plasma cells infiltration].
Zhonghua bing li xue za zhi = Chinese journal of pathologyGastrointestinal: Esophageal squamous cell papilloma in a patient with Cronkhite-Canada syndrome.
Journal of gastroenterology and hepatologyCronkhite-Canada Syndrome: Sustained Clinical Response with Anti-TNF Therapy.
Case reports in medicineRecombinant Thrombomodulin Used to Successfully Treat Cronkhite-Canada Syndrome with Disseminated Intravascular Coagulation due to Sepsis in a Compromised Patient.
Internal medicine (Tokyo, Japan)Cronkhite-Canada Syndrome Associated with Metastatic Colon Cancer.
Case reports in gastroenterologyLong-lasting remission in a case of Cronkhite-Canada syndrome.
BMJ case reportsPanendoscopic characterization of Cronkhite-Canada syndrome.
Medical journal, Armed Forces IndiaCronkhite-Canada Syndrome Showing Good Early Response to Steroid Treatment.
The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chiClinical and Endoscopic Remission in a Patient With Cronkhite-Canada Syndrome.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological AssociationSirolimus in Refractory Cronkhite-Canada Syndrome and Focus on Standard Treatment.
Journal of investigative medicine high impact case reportsAn unusual case of hamartomatous polyposis with malignancy complication in a patient with ulcerative colitis treated with golimumab.
Acta gastro-enterologica BelgicaA Case of Adolescent Cronkhite-Canada Syndrome.
Gastroenterology researchCronkhite-Canada syndrome causing pouch outlet obstruction 5 years after roux-en-y gastric bypass.
Acta chirurgica BelgicaNail Matrix Pathology in Cronkhite-Canada Syndrome: The First Case Report.
The American Journal of dermatopathologyCronkhite-Canada syndrome associated with colon cancer metastatic to liver: A case report.
MedicineCronkhite-Canada Syndrome with a Major Duodenal Papillary Adenocarcinoma.
Internal medicine (Tokyo, Japan)Alopecia in Cronkhite-Canada syndrome.
The British journal of dermatologyCronkhite-Canada Syndrome: A Rare Cause of Chronic Diarrhea.
Gastroenterology research[Two cases of the rare Cronkhite-Canada syndrome].
Ugeskrift for laegerApplication of novel magnified single balloon enteroscopy for a patient with Cronkhite-Canada syndrome.
World journal of gastroenterology[Other polyposis syndrome -report from Japanese nationwide survey of Cronkhite-Canada syndrome].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterologyCase report-malignant transformation in Cronkhite-Canada syndrome polyp.
MedicineAlopecia areata incognita in Cronkhite-Canada syndrome.
The British journal of dermatologySteroid Responsive Mononeuritis Multiplex in the Cronkhite-Canada Syndrome.
Frontiers in neurologyCronkhite Canada syndrome complicated by pulmonary embolism-A case report.
International journal of surgery case reportsIntravenous Vitamin C Administered as Adjunctive Therapy for Recurrent Acute Respiratory Distress Syndrome.
Case reports in critical careEffectiveness of cyclosporine as a treatment for steroid-resistant Cronkhite-Canada syndrome; two case reports.
BMC gastroenterologyCronkhite-Canada syndrome polyps infiltrated with IgG4-positive plasma cells.
World journal of clinical casesSyndromic Gastric Polyps: At the Crossroads of Genetic and Environmental Cancer Predisposition.
Advances in experimental medicine and biologyCronkhite-Canada syndrome - A Case report.
Anticancer researchCronkhite-Canada Syndrome Complicated by Triple Primary Cancers.
Internal medicine (Tokyo, Japan)Anemia and Neutropenia in Copper-Deficient Patients: A Report of Two Cases and Literature Review.
Journal of the Medical Association of Thailand = Chotmaihet thangphaetCronkhite Canada Syndrome: Significant Response to Infliximab and a Possible Clue to Pathogenesis.
The American journal of gastroenterologyPolyps! Polyps! And More Polyps! - The First Case of Cronkhite-Canada Syndrome in Malaysia.
The Medical journal of MalaysiaSmall-bowel video capsule endoscopic findings of Cronkhite-Canada syndrome.
Gastrointestinal endoscopyCronkhite-Canada Syndrome: A Rare Cause of Chronic Diarrhoea in a Young Man.
Case reports in medicineCronkhite-Canada syndrome: a rare case report and literature review.
BMC gastroenterologyDifficult case of Cronkhite-Canada syndrome with small intestinal bacterial overgrowth, Clostridium difficile infection and polymyalgia rheumatica.
BMJ case reportsCronkhite- Canada syndrome; a case report and review of the literature.
Gastroenterology and hepatology from bed to benchPathology and Genetics of Syndromic Gastric Polyps.
International journal of surgical pathologyCases Report the Cronkhite-Canada Syndrome: Improving the Prognosis.
MedicineA Case of Cronkhite-Canada Syndrome with a Colitis-mimicking Endoscopic Presentation.
Journal of Crohn's & colitisEndoscopic and clinical evaluation of treatment and prognosis of Cronkhite-Canada syndrome: a Japanese nationwide survey.
Journal of gastroenterologyCronkhite-Canada syndrome: A rare disease presenting with dermatological and gastrointestinal manifestations.
The Australasian journal of dermatologyColonic polyposis syndromes--an experience from a tertiary centre in South India.
Indian journal of gastroenterology : official journal of the Indian Society of GastroenterologyCronkhite-Canada Syndrome (CCS)-A Rare Case Report.
Journal of clinical and diagnostic research : JCDRA case of recurrent Cronkhite-Canada syndrome containing colon cancer.
International surgeryAssociações
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Referências e fontes
Bases de dados externas citadas neste artigo
Publicações científicas
Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.
- Diarrhea-Associated Hypovolemic Shock due to Cronkhite-Canada Syndrome.
- Cronkhite-Canada syndrome.Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver· 2026· PMID 41390305mais citado
- A comprehensive literature-based analysis of prognosis in patients with Cronkhite-Canada syndrome.
- Cronkhite-Canada syndrome, hypothyroidism and positive autoantibodies: a case report.
- Cronkhite-Canada syndrome after corticosteroid and mesalazine treatment: A case report and 3-year follow-up.
- An Uncommon Cause of Refractory Chronic Diarrhea.
Bases de dados e fontes oficiais
Identificadores e referências canônicas usadas para montar este verbete.
- ORPHA:2930(Orphanet)
- OMIM OMIM:175500(OMIM)
- MONDO:0008283(MONDO)
- GARD:4427(GARD (NIH))
- Busca completa no PubMed(PubMed)
- Q1422034(Wikidata)
Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.
Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar
