[Construction of a membrane-anchored bifunctional growth factor mimetic and its application in organoid culture].

The Inherited Basis of Coronary Artery Disease.

An oral nanocombinatorial agent exhibits pleiotropic improvement in diabetic nephropathy via modulation of the SCAP/SREBPs pathway.

Role of liver X receptors in the pathogenesis and treatment of chronic liver disease (Review).

The Relationship Between Triglycerides and Coronary Artery Disease Stratified by Sex and High-Density Lipoprotein Cholesterol in Men and Women.

Identification of gemilukast as a bifunctional molecule with lipid-lowering and anti-inflammatory activities.

Statin prescription rates for prevention of atherosclerotic cardiovascular disease in adults 40-75 years old with type 1 diabetes.

Transcriptomic Insights Into Alzheimer's Disease: Differentially Expressed Genes and Cholesterol Metabolism.

Association of Serum Lipids with 10-Year CVD and All-Cause Mortality in Iranian Adults: A Prospective Cohort Study.

Dexmedetomidine inhibits fear memory consolidation via the astrocyte-specific Srebf1-Phgdh pathway in the prelimbic prefrontal cortex.

Plasma sterol profiling in autism spectrum disorder: insights from cerebrotendinous xanthomatosis screening and beyond.

Vitamin D3 as an immunomodulatory agent: molecular mechanisms, clinical translation, and precision therapeutic strategies.

Effect of circulating exosomal miRNA-122-3p on metabolic dysfunction-associated steatotic liver disease through impairing FGFR4 expression.

Plasma ceramide Cer24:0 and insulin resistance: associations with TyG and TG/HDL-C in a multicenter study of coronary artery disease cohorts.

Non-targeted metabolomics reveals metabolic signatures associated with Clostridioides difficile virulence.

Associations of cumulative exposure and dynamic trajectories of cholesterol-HDL-glucose (CHG) index with cardiovascular disease in middle-aged and older Chinese adults: a longitudinal analysis.

Germacrone suppresses renal cancer growth by regulating c-Fos-mediated lipid metabolism.

3'-Hydroxypterostilbene Alleviates Obesity and Lipoprotein Metabolism Dysregulation by Reshaping Gut Microbiota in High-Fat Diet-Induced Obese Mice.

Dysregulated Cholesterol Clearance via CYP46A1 Contributes to Cerebellar Sterol Imbalance in Mecp2-Null Mice.

Functional Foods as Vehicles for Bioactive Compounds: Chemical and Nutritional Perspectives on Health and Disease Prevention.

LDL Cholesterol Modulates Astrocyte Metabolism, Lipid Handling, and Morphology: Evidence From In Vitro and In Vivo Models.

[Traditional Chinese medicine improves glycolipid metabolism disorders caused by high-fat diet via regulating AMPK/FXR/TLR4 signal molecules through gut-liver axis].

Rosemary-derived triterpene acids improve growth and lipid metabolism in juvenile grass carp (Ctenopharyngodon idella) through the gut-liver axis by tissue-specifically regulating the farnesoid X receptor.

Endogenous calcitriol production and ionized hypercalcemia in 7 dogs with chronic dermatopathy of infectious and noninfectious etiology (2016-2024).

Nonlinear association of residual cholesterol to high-density lipoprotein cholesterol ratio with diabetes mellitus: a retrospective cohort study.

Association between the atherogenic index of plasma and acute kidney injury in sepsis patients.

Extracellular vesicles related to familial hypercholesterolemia.

Trajectories of metabolic risk clusters and adverse outcomes in patients with chronic kidney disease: a prospective cohort study in Taiwan.

A multi-target combinatorial therapy of MDBA alleviates atopic dermatitis via synchronized immunosuppression and barrier repair.

Elesclomol Promotes oxLDL-Mediated Foam Cell Formation and Cuproptosis in Macrophages.

OSBPL3-driven sterol metabolic reprogramming promotes oncogenic signaling and therapeutic resistance in pancreatic cancer.

Case report: The first report of a family with sitosterolemia in the Polish population.

Emerging role of 7-Ketocholesterol and hydroxylated 7-Ketocholesterol in the pathophysiology of disease.

F-53B triggers sleep disorders via very long-chain ceramide accumulation in Drosophila neurons.

Safety and Effectiveness of Pharmacy Compounded Chenodeoxycholic Acid Capsules for Patients With Cerebrotendinous Xanthomatosis.

Cardiometabolic index and cardiovascular disease incidence in middle-aged and older Chinese: A nationwide prospective cohort study.

[Modern treatment of type 2 diabetes: 3 medications and 3 targets].

American Heart Association's Life's Simple 7 for cardiovascular health assessment among Iranian adults: a national cross-sectional study from STEPwise approach to non-communicable diseases risk factor surveillance (STEPS) survey 2021.

Risk and all-cause mortality of high low-density lipoprotein cholesterol-albumin ratio level in stable coronary artery disease patients following percutaneous coronary intervention.

Association of VitD 3 deficiency with thyroid nodules suspected of malignancy in petroleum workers: a retrospective cohort study.

Daucosterol alleviates osteoarthritis by targeting chondrocyte senescence via inhibiting of the JNK pathway.

Evaluation of Urine Exosome Lecithin Cholesterol Acyltransferase as a Biomarker for Diabetes Diagnosis and Dyslipidemia.

Caveolin-1 regulates cellular cholesterol homeostasis and its potential as an atherosclerosis therapy target.

Impact of TyG index on coronary plaques in patients with coronary artery disease under aggressive lipid-lowering therapy.

7-Ketocholesterol promotes T cell migration through Ca2+-NFATc1 pathway-mediated F-actin polymerization and proinflammatory cytokine production in oral lichen planus.

Phellopterin from angelica dahurica is a natural antagonist of glucocorticoid receptors regulating lipid and cholesterol metabolism.

Structure-activity relationships of steroid and sterol neuromodulators on inflammatory markers in a murine microglial cell line.

FOXN3 integrates the KU70/KU80/SREBP-1 complex to regulate lipid metabolism in non-alcoholic fatty liver disease.

Computational exploration of Withania coagulans-derived natural inhibitors targeting HMG-CoA reductase: A pharmacokinetic, docking and molecular dynamics study for cholesterol regulation in Mus musculus.

Association between the remnant cholesterol inflammatory index and gallstone disease: A cross-sectional analysis based on NHANES 2017 to 2020.

Connecting glycation and lipotoxicity to mitochondrial dysfunction in diabetic kidney disease: A 'tubulocentric' perspective.

Feasibility of remnant cholesterol as a therapeutic target for atherosclerotic cardio-vascular disease.

Zebrafish screen of schizophrenia risk genes reveals convergent dysregulation of cholesterol metabolism.

The Role of Vitamin D3 in Periodontal Health: Implications for Bone Metabolism, Immune Modulation and Inflammation Control.

An ACOT4 Multi-Nucleotide Variant Is Associated with Cardiovascular Risk in Norfolk Island and UK Biobank Cohorts.

ABCA1: A Therapeutic Target for Improving Cholesterol Homeostasis in Peripheral Neuropathies.

Sex Differences on Social and Anxiety-Related Responses in Low-Density Lipoprotein Receptor Knockout Mice.

Amides from Porcelia ponderosa Roots Display Efficacy In Vitro Against Intracellular Amastigotes of Trypanosoma cruzi.

Regulation of ABC Transporters and Ergosterol Biosynthesis by the Transcription Factor FvADS-1 Controls Azole Resistance and Virulence in Fusarium verticillioides.

Membrane Dysfunction as a Central Mechanism in LRRK2-Associated Parkinson's Disease: Comparative Analysis of G2019S and I1371V Variants.

Deciphering the anti-atherosclerotic mechanisms of Danggui-Chuanxiong herb pair: a synergistic approach combining computational prediction and in vivo verification.

Pyelonephritis decreases serum cholesterol and mitigates atherosclerosis severity despite systemic inflammation.

ATF2-LPCAT1-mediated PKM2 acetylation links cholesterol stress to macrophage metabolic reprogramming and functional remodeling.

Baitouweng Tang alleviates dextran sulfate sodium-induced ulcerative colitis in mice: a network pharmacology combined with experimental study.

The cholesterol, high-density lipoprotein, and glucose (CHG) index as a novel metabolic marker for predicting adverse outcomes in myocardial infarction survivors: insights from two large prospective cohorts.

Investigating the prediction potential of cholesterol, high-density lipoprotein, and glucose index surpasses TyG, AIP, and METS-IR for type 2 diabetes: a longitudinal cohort study.

Sympathetic Nerve Activation Drives Cardiac Fibrosis and Arrhythmia in Lean Metabolic Dysfunction-Associated Steatohepatitis Mice Concurrently Exposed to Ethanol and a High-Fat/High-Cholesterol Diet.

Comprehensive analysis of Salvia uliginosa extract: HPLC-MS, GC-MS and evaluation of antioxidant and neuroprotective effects.

Lecithin-cholesterol acyltransferase deficiency with the finding of "zebra bodies": A diagnostic challenge in the context of suspected Fabry disease.

SREBP1-driven SCD1 protects retinal pigment epithelium from oxidative damage by activating the NRF2/GPX4 axis.

Evolution of triglyceride and total cholesterol levels after critical illness: Preliminary insights into post-ICU metabolic sequelae.

Determinants of extracellular fluid calcium concentration in patients with chronic hypoparathyroidism.

Age-related macular degeneration and cerebral amyloid angiopathy have similar pathologies from cholesterol-APOE-amyloid-β-complement mediated inflammation.

High-cholesterol-load-triggered pyroptosis of gingival fibroblasts promotes periodontitis.

Lamin B receptor upregulation in metastatic melanoma causes nuclear envelope fragility in confined migration during cancer invasion.

Farrerol ameliorates hepatic insulin resistance via AMPKα1/mTOR/SREBP-1 pathway: A study in T2DM rat models and palmitic acid-induced BRL 3 A hepatocytes.

Explaining clinically important variability in response to simvastatin treatment using a PBPK/PD approach.

3-Hydroxystearic acid promotes cholesterol efflux and attenuates atherosclerosis via the ALKBH5/PAX-8/ABCA1 pathway.

Vitamin D3 mediates amelioration of ulcerative colitis via the TRPV1-MAPK signaling pathway.

Resveratrol inhibits lipid deposition via JAML/Sirt1 pathway in podocytes.

APOE4 induces sex-dependent synaptic mitochondrial cholesterol, proteome, and respiratory function alterations in mice.

Clinical and genetic analysis of an early-onset sitosterolemia family caused by a novel compound heterozygous ABCG5 mutation.

Regulation of flagellar architecture and metabolic pathways associated with the Leishmania mexicana SUMO protease.

Squalene synthase induces ERα expression via cholesterol supplementation to confer statin resistance in lung cancer cells.

Hypercohin A alleviates hepatic steatosis via the mammalian target of rapamycin (mTOR)-dependent suppression of de novo lipogenesis and ferroptosis.

The evolving therapeutic landscape of PCSK9 inhibition.

Association of remnant cholesterol with cardiovascular events and mortality in biopsy-proven diabetic kidney disease.

Composition of Human Meibomian Gland Secretions: Insights from TOF-SIMS Analysis.

Ectopic FGFR1 Increases Intracellular Pool of Cholesterol in Prostate Cancer Cells.

Hepatic UGT2B-Mediated Testosterone Clearance Promotes Lipid Accumulation in High-Fat-Diet-Induced MASLD.

Sex Disparities in the Processes Underlying Aging: Mitochondrial DNA Copy Number Associations with Dynapenia, 25-Hydroxyvitamin D3 Levels and Quality of Life in Older Adults.

Targeting Pathways Implicated in Cholesterol Metabolism for Novel Cancer Therapy.

lncRNA MALAT1-mediated regulation of cholesterol-oxidative stress-iron metabolic dysregulation by paeoniflorin in osteoarthritic chondrocytes.

Myopathy and ataxia related to impaired mitochondrial function in mevalonate kinase deficiency.

Bis(monoacylglycero)phosphate protects murine RAW 264.7 macrophages against 7-Ketocholesterol-induced apoptosis and impaired autophagy.

The predictive potential of surrogate indicators of insulin resistance for type 2 diabetic kidney disease.

Residual inflammatory risk and clinical outcomes after contemporary percutaneous coronary intervention: a systematic review and meta-analysis.

Targeting excessive cholesterol deposition alleviates secondary lymphoedema.

Taraxasterol ameliorates bone loss of ovariectomized mice via suppressing the NLRP3 inflammasome and modulating the gut microbiota.

Efficacy of evinacumab by genotype and low-density lipoprotein receptor function in patients with homozygous familial hypercholesterolaemia: A subanalysis from the ELIPSE open-label extension study.

Amyloid β-Cholesterol Interplay: Removal of Cholesterol From the Membranes to Catalyze Aggregation and Amyloid Pathology.

Hypolipidemic activity of Limosilactobacillus fermentum SHY0004 from Miao sour soup.

Association of remnant cholesterol inflammation index with future cardiovascular disease risk in patients with cardiovascular-kidney-metabolic syndrome stages 0-3.

Insights to HDL dysfunctionality: hypothesis of exhausted HDL.

Oxytocin Attenuates Metabolic Dysfunction-associated Steatotic Liver Disease via AMPK/SREBP1c/FAS-mediated Suppression of Hepatic Lipogenesis.

Evaluating the Link Between High-Density Lipoprotein-Related Inflammatory Indices and Gallstone Disease in U.S. Adults.

Low HDL cholesterol is associated with elevated TNFR1 and TNFR2 levels in early diabetic kidney disease.

Associations between neutrophil-to-high-density lipoprotein cholesterol ratio and albuminuria: A cross-sectional study.

Cholesterol Lowering Alone Fails to Reverse Atherosclerotic Plaque Necrosis, Granulopoiesis, and Neurovascular Neutrophils in Middle-Aged Mice.

Lipidic contents within calcified plaques: Characteristics and response to LDL-C<55 mg/dL on multi-modality imaging.

Simvastatin Ameliorates Lipid Metabolism-Mediated Endothelial Inflammation and Tight Junction Impairment in Chronic Cerebral Hypoperfusion.

Lipid Keratopathy in Sitosterolemia: A Case Report and Review of The Ophthalmic Manifestations.

A Two Birds with One Stone Strategy: Sialic Acid-Modified Pitavastatin Liposomes for Combating Atherosclerosis and Tumors.

A phenome-wide hunt for risk factors of Alzheimer's disease: from metabolic clues to neuroimaging evidence.

Analysis of metabolic status and risk factors of small for gestational age children with catch-up growth in East China.

Unraveling the mechanistic links between blood pressure regulation and calcium-magnesium homeostasis: Insights into hypertension, hyperparathyroidism, and mineral disorders.

The Role of Testosterone in Atherosclerosis: View From Cell Cultures and Animal Models.

Downmodulation of cholesterol biosynthetic network governs activation of the innate immune response to Japanese encephalitis virus infection.

Paeoniflorin Ameliorates Metabolic Dysfunction-Associated Steatotic Liver Disease by SYK/SH3BP2 Signaling Pathway.

Therapeutic effects of vitamin D and intermittent fasting on metabolic associated steatotic liver disease in rats.

Gut microbiota-dependent 24-hydroxycholesterol metabolism contributes to capsaicin-induced amelioration of Alzheimer's disease-like pathology in mice.

Liver specific-inhibition of LPCAT3 ameliorates metabolic dysfunction-associated steatotic liver disease.

Association between ketogenic diet and cognitive function in older adults: The mediating role of neutrophil to high-density lipoprotein cholesterol ratio.

Malassezia globosa lipidome: The dynamics of uptake and secreted lipids.

A novel exopolysaccharide from Lactiplantibacillus plantarum H6 improves cholesterol metabolism via Muribaculum-mediated activation of the enterohepatic FXR-FGF15 axis.

Ganoderic Acid A alleviates ulcerative colitis by inhibiting the interleukin17 signaling pathway via targeting retinoic acid-related orphan receptor alpha.

GC-MS correlated-antiepileptic screening for probable GABA-modulator by PTZ-induced acute seizure model in Swiss albino mice and phytochemical profiling of ethanol extract of Ficus benghalensis.

A genome-wide association meta-analysis of cholesterol synthesis intermediates identifies three associations for lanosterol.

Effects of the FXR agonist GW4064 on metabolic disorders in db/db mice.

Beyond bile acids synthesis: metabolomics profiling highlights extensive metabolic dysregulation and treatment response in CTX.

LCA and 3-oxo-LCA mitigate dietary oxysterols-induced loss of barrier function in intestinal epithelial cells.

Cenobamate beyond Epilepsy: exploring associations with vascular risk factors through serological markers.

Unraveling cholesterol metabolism in multiple sclerosis: Gender-specific patterns and predictive biomarkers.

The MALDI Method to Analyze the Lipid Profile, Including Cholesterol, Triglycerides and Other Lipids.

Engineered macrophage-assisted atorvastatin nanotherapy for reversing foam cell formation in atherosclerosis.

Multiphasic Venture of Cholesterol Homeostasis: A Perspective on Statin Therapy.

LncRNA TUG1 promotes hepatic lipid accumulation by targeting the miR-29a-3p/SREBP-2/HMGCR axis in MAFLD.

Computational insights into oxysterols: MD and DFT applications in pharmaceutical research.

Sitosterolemia due to compound heterozygous mutations in ABCG5: a case report.

Ganoderic Acid A Modulates Enteric Neurons and Intestinal Homeostasis in Irritable Bowel Syndrome by Microbiota Sensing.

Structure and mechanism of the human bile acid transporter OSTα-OSTβ.

Loss of hepaCAM inhibits cholesterol biosynthesis and impairs learning and memory in mice.

The association between high-density lipoprotein cholesterol and depressive symptoms: The moderating role of inflammation.

Fenofibrate suppresses Mycoplasma bovis infection via autophagy-mediated cholesterol regulation in bovine mammary epithelial cells and murine mammary tissue.

Best Practices for the Nutritional Management of Infantile-Onset Lysosomal Acid Lipase Deficiency: A Case-Based Discussion.

Econazole Exhibits In Vitro and In Vivo Efficacy Against Leishmania amazonensis.

Enhanced Qualities of High-Density Lipoproteins (HDLs) with Antioxidant Abilities Are Associated with Lower Susceptibility of Hypertension in Middle-Aged Korean Participants: Impaired HDL Quality and Hypertension Risk.

Ferulic Acid Attenuates Heat Stress-Induced Hepatic and Intestinal Oxidative Stress and Cholesterol Metabolism Dysregulation in Juvenile Blunt Snout Bream (Megalobrama amblycephala).

Cholesterol Metabolism: An Ally in the Development and Progression of Cervical Cancer.

Very-Low-Density Lipoproteins Quantity but Not Composition Is Altered in Normotriglyceridemic Subjects with Elevated Lipoprotein (a) Level.

Complex I Modulator BI4500 Reduces MASH by Limiting Oxidative Stress and Reprogramming Lipid Metabolism via AMPK in MCD Rats.

Multi-Omics Analysis Identifies the Key Defence Pathways in Chinese Cabbage Responding to Black Spot Disease.

Lifelong cGAS deficiency leads to altered lipid storage and cholesterol homeostasis.

Development of a standardized murine model for investigating cholesterol crystallization and deposition in the gallbladder wall: effects of dietary cholesterol and pharmacological modulation.

Heteroduplex oligonucleotide technology boosts gene knockdown in cardiac and skeletal muscles.

E2F1-driven cholesterol synthesis via the SND1/ACLY axis potentiates malignant progression in prostate cancer.

ACTA2 Pathogenic Variants Activating Heat Shock Factor 1 and Increasing Cholesterol Biosynthesis in Smooth Muscle Cells Predispose to Early Onset Atherosclerosis.

Role of Mitochondrial Protein, mitoNEET, in Impaired Intracellular Cholesterol Metabolism-Induced Neuronal Cell Death.

Hepatic management of toxic sterols after acute deletion of Cyp51 from cholesterol synthesis.

Immune-metabolic dysregulation and suicide risk in adolescents with major depressive disorder: a cross-sectional study.

TREM2 expression level is critical for microglial state, metabolic capacity and efficacy of TREM2 agonism.

Natural polyketide enterocin inhibits ASGR1 to enhance cholesterol efflux and regulate hepatic lipid metabolism.

MicroRNA-96 inhibition retarded the progression of atherosclerotic plaques via FOXO1/CYP7A1 mediated cholesterol-bile acid metabolism pathway.

Development and validation of a logistic regression model for predicting menstrual irregularity using LDL-C and age in reproductive-aged women: An analysis of NHANES Data.

The many faces of cholesterol in autosomal dominant polycystic kidney disease.

Molecular mechanisms of Aflatoxin B1-Induced renal injury and the detoxification potential of Taraxasterol: A review.

Autophagy in lipid metabolism.

Insights into the Destabilizing Effect of Fluorinated Ethanol on Biomimetic Membranes.

Different response of plaque regression following achievement of LDL-C <1.8 mmol/L in obese and nonobese patients with diabetes and coronary artery disease: OPTIMAL sub-analysis.

SREBP1-mediated lipid metabolism reprogramming drives malignant progression and therapeutic resistance in HPSCC organoids and animal models.

Stigmasterol Glucoside, a Phytosterol Glycoside, Mitigates Systemic Inflammatory Response Syndrome and Liver Injury.

Role of Oxysterol-Binding Protein Family in Cholesterol Metabolism and Cancer Progression: A Review.

Gut microbiota, lipid metabolism, and PCOS: A Mendelian randomization and mediation analysis.

Severe hypercholesterolemia in a pediatric cohort: Familial homozygous and autosomal recessive hypercholesterolemia.

Metabolic activation of lumisterol to biologically active metabolites and their mechanism of action.

Synthesis of benzo[e][1,2,4]thiadiazine 1,1-dioxide derivatives and its potential applications in atherosclerosis.

Ultrabright Carbon Dots as an Emerging Fluorescent Probe for Multivalent Labeling and Highly Sensitive Detection of Extracellular Vesicles.

Daucosterol Targets PFKFB3 to Mitigates Sepsis-Induced Acute Lung Injury by Inhibiting Glycolysis and M1 Macrophage Polarization.

Effect of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibitors on Lipoprotein(a) Levels: An Umbrella Review of Meta-analyses of Randomized Controlled Trials.

Causal relationships of lipid metabolism in diabetic nephropathy risk: A two-sample Mendelian randomization study.

Endothelial JMJD1C drives pathological ocular neovascularization by activating SREBF2-dependent cholesterol biosynthesis.

A new type of lipid nanoparticles with sphingomyelin-induced active lipid raft structures for improved mRNA cellular uptake.

Determinants of circulating PCSK9 levels and the efficacy of PCSK9 inhibitor therapies in chronic kidney disease: a systematic review.

An oral, liver-restricted LXR inverse agonist for dyslipidemia: preclinical development and phase 1 trial.

Precision approach in apoA-I infusion trials: When CSL112 may actually work.

Skeletal Muscle Mass Modifies the Prognostic Impact of LDL Cholesterol in Chronic Heart Failure.

Fueling Disease: ACSS2 in Obesity-Associated Metabolic Disorders and Cancer Progression.

Antisense oligonucleotide targeting TARDBP-EGFR splicing axis inhibits progression of oral squamous cell carcinoma through ABCA1-regulated cholesterol efflux.

Sitosterolemia Presenting as Lipid Keratopathy and Xanthomas.

The metabolic mood: Cholesterol homeostasis as a convergence point for depression risk.

Cholesterol Deficiency Directs Autophagy-Dependent Secretion of Extracellular Vesicles.

Cholesterol-lowering effects of oats induced by microbially produced phenolic metabolites in metabolic syndrome: a randomized controlled trial.

Lipid-Lowering Therapies in Patients with Chronic Kidney Disease: A Perspective on High-Density Lipoprotein Cholesterol.

Low-dose galactose rebalances HBP-mTORC1-SREBP-1c signaling to suppress hepatic lipogenesis and protect against early-stage alcohol-related liver disease.

Novel metabolic syndrome subgroups and their association with cardiovascular outcomes: A data-driven cluster analysis of the UK Biobank.

INSIG1 parallel substitution drives lipid/sterol metabolic plasticity mediating desert adaptation in ungulates.

Hematological, biochemical and hormonal profiles in dogs with obesity-related metabolic disorder.

Myeloid Fmr1 deficiency in mice results in reduced serum cholesterol and altered bile pathway gene expression.

Hepatocyte SAMHD1 Deficiency Attenuates Hepatic Steatosis via Suppression of SREBP Activation in a Mouse Model of Metabolic-Associated Steatotic Liver Disease.

Predictive value of remnant cholesterol inflammatory index for cardiovascular-kidney-metabolic syndrome progression: A prospective cohort study.